Carcinogenesis is a multistep process triggered by genetic alterations that activate different
signal transduction pathways and cause the progressive transformation of a normal cell into …

Flavonoids are a large group of polyphenolic compounds, which are ubiquitously expressed
in plants. They are grouped according to their chemical structure and function into flavonols, …

Aberrant Hedgehog (Hh)/glioma-associated oncogene (GLI) signaling has been implicated
in cancer progression. Here, we analyzed GLI1, Sonic Hedgehog (Shh) and NF-κB …

Cardiovascular diseases are the main cause of mortality and morbidity in the world.
Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart failure …

The survival rate of head and neck squamous cell carcinomas (HNSCC) patients has not
considerably changed over the last two decades. Polyphenols inhibit the growth of cancer cells…

Malignant mesothelioma (MM) is a primary tumor arising from the serous membranes. The
resistance of MM patients to conventional therapies, and the poor patients’ survival, …

In recent years, terahertz (THz) radiation has been widely used in a variety of applications:
medical, security, telecommunications and military areas. However, few data are available on …

Violacein (VIO; 3-[1,2-dihydro-5-(5-hydroxy-1H-indol-3-yl)-2-oxo-3H-pyrrol-3-ylidene]-1,3-dihydro-2H-indol-2-one),
an indole-derived purple-colored pigment, produced by a limited …

Polyphenols are natural antioxidant compounds ubiquitously found in plants and, thus, ever
present in human nutrition (tea, wine, chocolate, fruits and vegetables are typical examples …

Breast cancer is a leading cancer in women and dèspite the benefits of the current therapies
a signifìcant number of patients with this tumor is at risk of relapse. Some of the alterations …