Presenilins and mitochondria—an intriguing link: mini-review

M Makarov, L Kushnireva, M Papa… - Frontiers in …, 2023 - frontiersin.org
This review uncovers the intricate relationship between presenilins, calcium, and mitochondria
in the context of Alzheimer’s disease (AD), with a particular focus on the involvement of …

Differential role of active compounds in mitophagy and related neurodegenerative diseases

M Makarov, E Korkotian - Toxins, 2023 - mdpi.com
Neurodegenerative diseases, such as Alzheimer’s disease or Parkinson’s disease, significantly
reduce the quality of life of patients and eventually result in complete maladjustment. …

Computational Modeling of Extrasynaptic NMDA Receptors: Insights into Dendritic Signal Amplification Mechanisms

M Makarov, M Papa, E Korkotian - International Journal of Molecular …, 2024 - mdpi.com
Dendritic structures play a pivotal role in the computational processes occurring within
neurons. Signal propagation along dendrites relies on both passive conduction and active …

Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome

EM Makarov, OV Makarova, H Urlaub, M Gentzel… - Science, 2002 - science.org
… The restructured U5 complex persists without marked change in composition through both
catalytic steps of splicing until it is released, initially together with U2 and U6 as part of the …

Electrostatic axially harmonic orbital trapping: a high-performance technique of mass analysis

A Makarov - Analytical chemistry, 2000 - ACS Publications
This work describes a new type of mass analyzer which employs trapping in an electrostatic
field. The potential distribution of the field can be represented as a combination of …

A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing

OV Makarova, EM Makarov, H Urlaub, CL Will… - The EMBO …, 2004 - embopress.org
During catalytic activation of the spliceosome, snRNP remodeling events occur, leading to
the formation of a 35S U5 snRNP that contains a large group of proteins, including Prp19 and …

[BOOK][B] Single molecule science: physical principles and models

DE Makarov - 2015 - books.google.com
The observation and manipulation of individual molecules is one of the most exciting
developments in modern molecular science, and the utility of single-molecule methods has proven …

Scattering of Ultrashort X-ray Pulses from Oriented NV Centers in the Diamond Structure

D Makarov, M Eseev, E Gusarevich, V Matveev… - Crystals, 2024 - mdpi.com
It is well known that the basis of diffraction analysis of matter is scattering, including the
scattering of ultrashort laser pulses. In the theory of scattering of ultrashort pulses, the pulse …

Disentanglement of local field potential sources by independent component analysis

VA Makarov, J Makarova, O Herreras - Journal of computational …, 2010 - Springer
The spontaneous activity of working neurons yields synaptic currents that mix up in the
volume conductor. This activity is picked up by intracerebral recording electrodes as local field …

Theory of HOM interference on coupled waveguides

DN Makarov - Optics Letters, 2020 - opg.optica.org
It is well known that the Hong–Ou–Mandel (HOM) effect can be realized on beam splitters (BSs)
in the form of coupled waveguides. It is believed that in this case, the theory is similar to …