The noise power spectrum of CT images

MF Kijewski, PF Judy - Physics in Medicine & Biology, 1987 - iopscience.iop.org
An expression for the noise power spectrum of images reconstructed by the discrete filtered
backprojection algorithm has been derived. The formulation explicitly includes sampling …

Quantitative dynamic cardiac 82Rb PET using generalized factor and compartment analyses

…, A Sitek, B Guérin, MF Kijewski… - Journal of nuclear …, 2005 - jnm.snmjournals.org
We have addressed 2 major challenges of 82 Rb cardiac PET, noninvasive estimation of an
accurate input function and absolute quantitation of myocardial perfusion, using a …

Cardiac Amyloid Quantification Using 124I-Evuzamitide (124I-P5+14) Versus 18F-Florbetapir: A Pilot PET/CT Study

…, JC Neri, V Chemburkar, MF Kijewski… - Cardiovascular …, 2023 - jacc.org
Background Cardiac amyloid quantification could advance early diagnosis of amyloid
cardiomyopathy (CMP) and treatment monitoring. However, current imaging tools are based on …

Relative apical sparing of myocardial longitudinal strain is explained by regional differences in total amyloid mass rather than the proportion of amyloid deposits

PE Bravo, K Fujikura, MF Kijewski… - JACC: Cardiovascular …, 2019 - jacc.org
Objectives : This study sought to test whether relative apical sparing (RELAPS) of left
ventricular (LV) longitudinal strain (LS) in cardiac amyloidosis (CA) is explained by regional …

Improved quantification of cardiac amyloid burden in systemic light chain amyloidosis: redefining early disease?

…, PE Bravo, RH Falk, S El-Sady, MF Kijewski… - Cardiovascular …, 2020 - jacc.org
Objectives The purpose of this study was to determine phenotypes characterizing cardiac
involvement in AL amyloidosis by using direct (fluorine-18-labeled florbetapir {[ 18 F]florbetapir…

Accuracy and reproducibility of myocardial blood flow quantification by single photon emission computed tomography imaging in patients with known or suspected …

…, VR Taqueti, M Foley Kijewski… - Circulation …, 2022 - ahajournals.org
Background: Single photon emission computed tomography (SPECT) has limited ability to
identify multivessel and microvascular coronary artery disease. Gamma cameras with …

Molecular imaging of systemic and cardiac amyloidosis: recent advances and focus on the future

S Dorbala, MF Kijewski - Journal of Nuclear Medicine, 2023 - jnm.snmjournals.org
Myocardial infiltration by amyloid fibrils causes a severe and progressive form of heart
failure. Until recently, this was not treatable. Several novel therapies have recently become …

Quantification of right ventricular amyloid burden with 18F-florbetapir positron emission tomography/computed tomography and its association with right ventricular …

…, H Landau, R Liao, MF Kijewski… - European Heart …, 2024 - academic.oup.com
Aims In systemic light-chain (AL) amyloidosis, quantification of right ventricular (RV) amyloid
burden has been limited and the pathogenesis of RV dysfunction is poorly understood. …

Quantitative 99mTc-pyrophosphate myocardial uptake: changes on transthyretin stabilization therapy

…, Y Gu, C Watts, K Sullivan, B Auer, MF Kijewski… - Journal of Nuclear …, 2024 - Elsevier
Background Quantitative technetium-99m-pyrophosphate cardiac single-photon emission
computed tomography ( 99m Tc-PYP SPECT/CT) is an emerging method for estimating …

Prognostic Value of Left Ventricular 18F-Florbetapir Uptake in Systemic Light-Chain Amyloidosis

…, A Taylor, DC Benz, M Robertson, MF Kijewski… - Cardiovascular …, 2024 - jacc.org
Background Positron emission tomography/computed tomography (PET/CT) with 18 F-florbetapir,
a novel amyloid-targeting radiotracer, can quantify left ventricular (LV) amyloid burden …