Identification of RdRp inhibitors against SARS-CoV-2 through E-pharmacophore-based virtual screening, molecular docking and MD simulations approaches

…, K Shinwari, MA Bhinder, MU Ghani, M Saleem… - International Journal of …, 2023 - Elsevier
The outbreak of novel Coronavirus, an enduring pandemic declared by WHO, has
consequences to an alarming ongoing public health menace which has already claimed several …

[HTML][HTML] Paromomycin: a potential dual targeted drug effectively inhibits both spike (S1) and main protease of COVID-19

A Tariq, RM Mateen, MS Afzal, M Saleem - International Journal of …, 2020 - Elsevier
Objectives With the increasing number of people suffering from coronavirus disease 2019 (COVID-19),
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), …

Identification of NS2B-NS3 protease inhibitors for therapeutic application in ZIKV infection: A pharmacophore-based high-throughput virtual screening and MD …

…, N Hussain, ASA Said, AHI Al Haddad, M Saleem - Vaccines, 2023 - mdpi.com
Zika virus (ZIKV) pandemic and its implication in congenital malformations and severe
neurological disorders had created serious threats to global health. ZIKV is a mosquito-borne …

Glycosylated Alpha-1-acid glycoprotein 1 as a potential lung cancer serum biomarker

A Ayyub, M Saleem, I Fatima, A Tariq, N Hashmi… - The international journal …, 2016 - Elsevier
Presently existing screening approaches for lung cancer are not being proving sufficient
and sensitive, so a study was conducted to identify disease related biomarker proteins for …

[PDF][PDF] Saccharification of lignocellulosic materials by the cellulases of Bacillus subtilis

MS Akhtar, M Saleem, MW Akhtar - Int J Agric Biol, 2001 - researchgate.net
Cellulases produced by Bacillus (B.) subtilis were used for the saccharification of wheat straw,
rice straw and bagasse. Pretreatment of these substrates with 2% NaOH was found to be …

Potential of xylanase from thermophilic Bacillus sp. XTR-10 in biobleaching of wood kraft pulp

M Saleem, MR Tabassum, R Yasmin… - International …, 2009 - Elsevier
An extracellular xylanase produced under optimal conditions by a thermophilic strain of Bacillus
sp. XTR-10 was evaluated for its potential application in biobleaching of wood kraft pulp. …

Biochemical analysis and investigation on the prospective applications of alkaline protease from a Bacillus cereus strain

M Saleem, A Rehman, R Yasmin, B Munir - Molecular biology reports, 2012 - Springer
Proteases have prospective financial and environment-friendly applications; hence attention
is focused currently on the finding of new protease producing microorganism so as to meet …

Molecular Cloning, Expression, Sequence Characterization and Structural Insight of Bubalus bubalis Growth Hormone-Receptor

R Gul, MU Hanif, F Gul, HM Rehman, M Saleem… - Molecular …, 2023 - Springer
The current study focuses on molecular cloning, expression and structural characterization
of growth hormone-receptor (GHR) and its extracellular domain as growth hormone binding …

[HTML][HTML] Association of FcγRIIa polymorphism with clinical outcome of dengue infection: first insight from Pakistan

…, A Amar, F Ghafoor, SM Raza, M Saleem - The American journal …, 2015 - ncbi.nlm.nih.gov
Dengue illness has been a major health concern in Pakistan during the last decade. Dengue
infection can result in a spectrum of clinically distinct outcomes, ranging from asymptomatic …

A putative prophylactic solution for COVID-19: development of novel multiepitope vaccine candidate against SARS-COV-2 by comprehensive immunoinformatic and …

HM Rehman, MU Mirza, MA Ahmad, M Saleem… - Biology, 2020 - mdpi.com
Simple Summary COVID-19, caused by a novel coronavirus, SARS-CoV-2, first emerged in
China in December 2019, and then spread around the globe with more than 29 million …