The spliceosome removes introns from messenger RNA precursors (pre-mRNA). Decades
of biochemistry and genetics combined with recent structural studies of the spliceosome …

Nonsense-mediated mRNA decay (NMD) is a quality-control mechanism that selectively
degrades mRNAs harboring premature termination (nonsense) codons. If translated, these …

In an often rapidly changing environment, cells must adapt by monitoring and reacting
quickly to extracellular stimuli detected by membrane‐bound receptors and proteins …

There is an urgent need to improve the infrastructure supporting the reuse of scholarly data.
A diverse set of stakeholders—representing academia, industry, funding agencies, and …

High-quality and complete reference genome assemblies are fundamental for the
application of genomics to biology, disease, and biodiversity conservation. However, such …

The Bioperl project is an international open-source collaboration of biologists,
bioinformaticians, and computer scientists that has evolved over the past 7 yr into the most …

The evidentiary basis of the currently accepted classification of living amphibians is
discussed and shown not to warrant the degree of authority conferred on it by use and …

DNA barcoding involves sequencing a standard region of DNA as a tool for species
identification. However, there has been no agreement on which region (s) should be used …

Background The prevalence and spectrum of predisposing mutations among children and
adolescents with cancer are largely unknown. Knowledge of such mutations may improve …

The present guideline summarizes all aspects of patch testing for the diagnosis of contact
allergy in patients suspected of suffering, or having been suffering, from allergic contact …