Infection is restrained by the concerted activation of tissue-resident and circulating immune
cells. Whether tissue-resident lymphocytes confer early antiviral immunity at local sites of …

Although COVID-19 is considered to be primarily a respiratory disease, SARS-CoV-2 affects
multiple organ systems including the central nervous system (CNS). Yet, there is no …

Saliva or Nasopharyngeal Swab Specimens for Detection of SARS-CoV-2 | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

The recent spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
exemplifies the critical need for accurate and rapid diagnostic assays to prompt clinical and …

Rapid and accurate SARS-CoV-2 diagnostic testing is essential for controlling the ongoing
COVID-19 pandemic. The current gold standard for COVID-19 diagnosis is real-time RT …

Cytokines were the first modern immunotherapies to produce durable responses in patients
with advanced cancer, but they have only modest efficacy and limited tolerability,. In an effort …

Innate lymphoid cells (ILCs) function to protect epithelial barriers against pathogens and
maintain tissue homeostasis in both barrier and non-barrier tissues. Here, utilizing Eomes …

Clonal expansion and immunological memory are hallmark features of the mammalian
adaptive immune response and essential for prolonged host control of pathogens. Recent …

Innate lymphoid cells (ILCs) are tissue-resident sentinels that are essential for early host
protection from pathogens at initial sites of infection. However, whether pathogen-derived …

Telomeres repress the DNA damage response at the natural chromosome ends to prevent
cell-cycle arrest and maintain genome stability. Telomeres are elongated by telomerase in a …