Progressive hepatolenticular degeneration, or Wilson's disease, is a genetic disorder of
copper metabolism. Knowledge of the clinical presentations and treatment of the disease …

This overview paper describes the legacy prospect and discovery potential of the Dark
Energy Survey (DES) beyond cosmological studies, illustrating it with examples from the …

Atmospheric carbon dioxide concentration ([CO2]) is increasing, which increases leaf‐scale
photosynthesis and intrinsic water‐use efficiency. These direct responses have the potential …

Background Mortality statistics are fundamental to public health decision making. Mortality
varies by time and location, and its measurement is affected by well known biases that have …

Abstract Coronavirus disease 2019 (COVID-19) has rapidly affected mortality worldwide.
There is unprecedented urgency to understand who is most at risk of severe outcomes, and …

Sterol regulatory element-binding proteins (SREBPs) activate genes involved in the
synthesis and trafficking of cholesterol and other lipids and are critical for maintaining lipid …

To determine the risk of active tuberculosis associated with human immunodeficiency virus
(HIV) infection, we prospectively studied 520 intravenous drug users enrolled in a …

Accurate assessment of anthropogenic carbon dioxide (CO 2) emissions and their
redistribution among the atmosphere, ocean, and terrestrial biosphere–the “global carbon …

The populations of dominant species within the human colonic microbiota can potentially be
modified by dietary intake with consequences for health. Here we examined the influence of …

Background The study of microbial communities has been revolutionised in recent years by
the widespread adoption of culture independent analytical techniques such as 16S rRNA …