User profiles for "author:Waghray A"

Avinash Waghray, PhD

Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical …
Verified email at mgh.harvard.edu
Cited by 7467

Vanadium in the detection, prevention and treatment of cancer: the in vivo evidence

A Bishayee, A Waghray, MA Patel, M Chatterjee - Cancer Letters, 2010 - Elsevier
Vanadium, a dietary micronutrient, is yet to be established as an essential part of the human
diet. Over the past century, several biological effects of vanadium, such as insulin-mimetic …

The human lung cell atlas: a high-resolution reference map of the human lung in health and disease

HB Schiller, DT Montoro, LM Simon… - American journal of …, 2019 - atsjournals.org
Lung disease accounts for every sixth death globally. Profiling the molecular state of all lung
cell types in health and disease is currently revolutionizing the identification of disease …

[PDF][PDF] The role of tissue transglutaminase in cell-matrix interactions

EA Zemskov, A Janiak, J Hang, A Waghray… - Front Biosci, 2006 - researchgate.net
Introduction 3. Cell surface tTG and its non-enzymatic function in cell-matrix adhesion 3.1.
tTG-FN interaction 3.2. Association of tTG with integrins 3.3. Other molecular interactions of …

[HTML][HTML] SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues

CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao… - Cell, 2020 - cell.com
There is pressing urgency to understand the pathogenesis of the severe acute respiratory
syndrome coronavirus clade 2 (SARS-CoV-2), which causes the disease COVID-19. SARS …

COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

TM Delorey, CGK Ziegler, G Heimberg, R Normand… - Nature, 2021 - nature.com
COVID-19, which is caused by SARS-CoV-2, can result in acute respiratory distress
syndrome and multiple organ failure,,–, but little is known about its pathophysiology. Here …

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

DT Montoro, AL Haber, M Biton, V Vinarsky, B Lin… - Nature, 2018 - nature.com
The airways of the lung are the primary sites of disease in asthma and cystic fibrosis. Here
we study the cellular composition and hierarchy of the mouse tracheal epithelium by single …

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

X Carvajal-Vergara, A Sevilla, SL D'Souza, YS Ang… - Nature, 2010 - nature.com
The generation of reprogrammed induced pluripotent stem cells (iPSCs) from patients with
defined genetic disorders holds the promise of increased understanding of the aetiologies of …

Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics

C Muus, MD Luecken, G Eraslan, L Sikkema… - Nature medicine, 2021 - nature.com
Abstract Angiotensin-converting enzyme 2 (ACE2) and accessory proteases (TMPRSS2 and
CTSL) are needed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

M Slyper, CBM Porter, O Ashenberg, J Waldman… - Nature medicine, 2020 - nature.com
Single-cell genomics is essential to chart tumor ecosystems. Although single-cell RNA-Seq
(scRNA-Seq) profiles RNA from cells dissociated from fresh tumors, single-nucleus RNA …

Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions

MR Filbin, A Mehta, AM Schneider, KR Kays… - Cell Reports …, 2021 - cell.com
Mechanisms underlying severe coronavirus disease 2019 (COVID-19) disease remain
poorly understood. We analyze several thousand plasma proteins longitudinally in 306 …