Resurgence of Ebola virus in 2021 in Guinea suggests a new paradigm for outbreaks

AK Keita, FR Koundouno, M Faye, A Düx, J Hinzmann… - Nature, 2021 - nature.com
Seven years after the declaration of the first epidemic of Ebola virus disease in Guinea, the
country faced a new outbreak—between 14 February and 19 June 2021—near the …

Virucidal activity of World Health Organization–recommended formulations against enveloped viruses, including Zika, Ebola, and emerging coronaviruses

A Siddharta, S Pfaender, NJ Vielle… - The Journal of …, 2017 - academic.oup.com
Abstract The World Health Organization (WHO) published 2 alcohol-based formulations to
be used in healthcare settings and for outbreak-associated infections, but inactivation …

A prospective, multi-site, cohort study to estimate incidence of infection and disease due to Lassa fever virus in West African countries (the Enable Lassa research …

S Penfold, AA Adegnika, D Asogun, O Ayodeji… - PloS one, 2023 - journals.plos.org
Background Lassa fever (LF), a haemorrhagic illness caused by the Lassa fever virus
(LASV), is endemic in West Africa and causes 5000 fatalities every year. The true …

Silent infection of human dendritic cells by African and Asian strains of Zika virus

NJ Vielle, B Zumkehr, O García-Nicolás, F Blank… - Scientific reports, 2018 - nature.com
While Zika virus (ZIKV) circulated for decades (African lineage strains) without report of
outbreaks and severe complications, its emergence in French Polynesia and subsequently …

[HTML][HTML] Research models and tools for the identification of antivirals and therapeutics against Zika virus infection

MP Alves, NJ Vielle, V Thiel, S Pfaender - Viruses, 2018 - mdpi.com
Zika virus recently re-emerged and caused global outbreaks mainly in Central Africa,
Southeast Asia, the Pacific Islands and in Central and South America. Even though there is …

Virulence and genotype-associated infectivity of interferon-treated macrophages by porcine reproductive and respiratory syndrome viruses

O García-Nicolás, A Baumann, NJ Vielle… - Virus research, 2014 - Elsevier
The polarization into M1 and M2 macrophages (MΦ) is essential to understand MΦ function.
Consequently, the aim of this study was to determine the impact of IFN-γ (M1), IL-4 (M2) and …

A Japanese encephalitis virus vaccine inducing antibodies strongly enhancing in vitro infection is protective in pigs

O García-Nicolás, ME Ricklin, M Liniger, NJ Vielle… - Viruses, 2017 - mdpi.com
The Japanese encephalitis virus (JEV) is responsible for zoonotic severe viral encephalitis
transmitted by Culex mosquitoes. Although birds are reservoirs, pigs play a role as …

Comparison of innate immune responses towards rhinovirus infection of primary nasal and bronchial epithelial cells

MP Alves, A Schögler, S Ebener, NJ Vielle… - …, 2016 - Wiley Online Library
Background and objective Rhinoviruses (RV) replicate in both upper and lower airway
epithelial cells. We evaluated the possibility of using nasal epithelial cells (NEC) as …

The human upper respiratory tract epithelium is susceptible to flaviviruses

NJ Vielle, O García-Nicolás… - Frontiers in …, 2019 - frontiersin.org
Flaviviruses replicate in a wide variety of species and have a broad cellular tropism. They
are isolated from various body fluids, and Zika virus (ZIKV), Japanese encephalitis virus …

[HTML][HTML] Inactivation of Zika virus in human breast milk by prolonged storage or pasteurization

S Pfaender, NJ Vielle, N Ebert, E Steinmann, MP Alves… - Virus research, 2017 - Elsevier
Zika virus infection during pregnancy poses a serious risk for pregnant women as it can
cause severe birth defects. Even though the virus is mainly transmitted via mosquitos …