Neuroinvasion of SARS-CoV-2 in human and mouse brain
Although COVID-19 is considered to be primarily a respiratory disease, SARS-CoV-2 affects
multiple organ systems including the central nervous system (CNS). Yet, there is no …
multiple organ systems including the central nervous system (CNS). Yet, there is no …
SARS–CoV-2 infection of the placenta
H Hosier, SF Farhadian, RA Morotti, U Deshmukh… - The Journal of clinical …, 2020 - jci.org
BACKGROUND The effects of the novel coronavirus disease 2019 (COVID-19) in pregnancy
remain relatively unknown. We present a case of second trimester pregnancy with …
remain relatively unknown. We present a case of second trimester pregnancy with …
Hypothalamic POMC neurons promote cannabinoid-induced feeding
M Koch, L Varela, JG Kim, JD Kim, F Hernández-Nuño… - Nature, 2015 - nature.com
Hypothalamic pro-opiomelanocortin (POMC) neurons promote satiety. Cannabinoid
receptor 1 (CB1R) is critical for the central regulation of food intake. Here we test whether …
receptor 1 (CB1R) is critical for the central regulation of food intake. Here we test whether …
[HTML][HTML] Astrocytic insulin signaling couples brain glucose uptake with nutrient availability
We report that astrocytic insulin signaling co-regulates hypothalamic glucose sensing and
systemic glucose metabolism. Postnatal ablation of insulin receptors (IRs) in glial fibrillary …
systemic glucose metabolism. Postnatal ablation of insulin receptors (IRs) in glial fibrillary …
Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding
JG Kim, S Suyama, M Koch, S Jin… - Nature …, 2014 - nature.com
We found that leptin receptors were expressed in hypothalamic astrocytes and that their
conditional deletion led to altered glial morphology and synaptic inputs onto hypothalamic …
conditional deletion led to altered glial morphology and synaptic inputs onto hypothalamic …
Nucleus reuniens of the midline thalamus: link between the medial prefrontal cortex and the hippocampus
The medial prefrontal cortex and the hippocampus serve well recognized roles in memory
processing. The hippocampus projects densely to, and exerts strong excitatory actions on …
processing. The hippocampus projects densely to, and exerts strong excitatory actions on …
Zika virus disrupts phospho-TBK1 localization and mitosis in human neuroepithelial stem cells and radial glia
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other
neurodevelopment defects remain poorly understood. Here, we describe the derivation and …
neurodevelopment defects remain poorly understood. Here, we describe the derivation and …
Vaginal exposure to Zika virus during pregnancy leads to fetal brain infection
Zika virus (ZIKV) can be transmitted sexually between humans. However, it is unknown
whether ZIKV replicates in the vagina and impacts the unborn fetus. Here, we establish a …
whether ZIKV replicates in the vagina and impacts the unborn fetus. Here, we establish a …
Bisphenol A prevents the synaptogenic response to estradiol in hippocampus and prefrontal cortex of ovariectomized nonhuman primates
C Leranth, T Hajszan, K Szigeti-Buck, J Bober… - Proceedings of the …, 2008 - pnas.org
Exposure measurements from several countries indicate that humans are routinely exposed
to low levels of bisphenol A (BPA), a synthetic xenoestrogen widely used in the production of …
to low levels of bisphenol A (BPA), a synthetic xenoestrogen widely used in the production of …
Intranasal epidermal growth factor treatment rescues neonatal brain injury
There are no clinically relevant treatments available that improve function in the growing
population of very preterm infants (less than 32 weeks' gestation) with neonatal brain injury …
population of very preterm infants (less than 32 weeks' gestation) with neonatal brain injury …