User profiles for "author:Syed A"

Aijazuddin Syed - Verified email at mskcc.org - Cited by 9431
Abdullah Muhammad Syed - Verified email at gladstone.ucsf.edu - Cited by 4955
Affan Syed - Verified email at emumba.com - Cited by 3812

Metal‐based nanoparticles and their toxicity assessment

AM Schrand, MF Rahman, SM Hussain… - Wiley …, 2010 - Wiley Online Library
Nanoparticles (NPs) can potentially cause adverse effects on organ, tissue, cellular,
subcellular, and protein levels due to their unusual physicochemical properties (eg, small …

Research challenges and applications for underwater sensor networking

J Heidemann, W Ye, J Wills, A Syed… - … , 2006. WCNC 2006., 2006 - ieeexplore.ieee.org
This paper explores applications and challenges for underwater sensor networks. We
highlight potential applications to off-shore oilfields for seismic monitoring, equipment …

The MRE11–RAD50–NBS1 complex conducts the orchestration of damage signaling and outcomes to stress in DNA replication and repair

A Syed, JA Tainer - Annual review of biochemistry, 2018 - annualreviews.org
Genomic instability in disease and its fidelity in health depend on the DNA damage
response (DDR), regulated in part from the complex of meiotic recombination 11 homolog 1 …

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

A Zehir, R Benayed, RH Shah, A Syed, S Middha… - Nature medicine, 2017 - nature.com
Tumor molecular profiling is a fundamental component of precision oncology, enabling the
identification of genomic alterations in genes and pathways that can be targeted …

Rapid assessment of SARS-CoV-2–evolved variants using virus-like particles

AM Syed, TY Taha, T Tabata, IP Chen, A Ciling… - Science, 2021 - science.org
Efforts to determine why new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) variants demonstrate improved fitness have been limited to analyzing mutations in the …

[HTML][HTML] Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): a hybridization capture-based next-generation …

DT Cheng, TN Mitchell, A Zehir, RH Shah… - The Journal of molecular …, 2015 - Elsevier
The identification of specific genetic alterations as key oncogenic drivers and the
development of targeted therapies are together transforming clinical oncology and creating …

The entry of nanoparticles into solid tumours

S Sindhwani, AM Syed, J Ngai, BR Kingston… - Nature materials, 2020 - nature.com
The concept of nanoparticle transport through gaps between endothelial cells (inter-
endothelial gaps) in the tumour blood vessel is a central paradigm in cancer nanomedicine …

[HTML][HTML] Effect of vitamin C infusion on organ failure and biomarkers of inflammation and vascular injury in patients with sepsis and severe acute respiratory failure: the …

AA Fowler III, JD Truwit, RD Hite, PE Morris… - Jama, 2019 - pmc.ncbi.nlm.nih.gov
Importance Experimental data suggest that intravenous vitamin C may attenuate
inflammation and vascular injury associated with sepsis and acute respiratory distress …

Clinical sequencing defines the genomic landscape of metastatic colorectal cancer

R Yaeger, WK Chatila, MD Lipsyc, JF Hechtman… - Cancer cell, 2018 - cell.com
Metastatic colorectal cancers (mCRCs) are clinically heterogeneous, but the genomic basis
of this variability remains poorly understood. We performed prospective targeted sequencing …

IoT in smart cities: A survey of technologies, practices and challenges

AS Syed, D Sierra-Sosa, A Kumar, A Elmaghraby - Smart Cities, 2021 - mdpi.com
Internet of Things (IoT) is a system that integrates different devices and technologies,
removing the necessity of human intervention. This enables the capacity of having smart (or …