User profiles for "author:Steain M"
 | Megan SteainThe University of Sydney Verified email at sydney.edu.au Cited by 2728 |
Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis
Summary Background Several SARS-CoV-2 variants of concern have been identified that
partly escape serum neutralisation elicited by current vaccines. Studies have also shown …
partly escape serum neutralisation elicited by current vaccines. Studies have also shown …
Manipulation of the innate immune response by varicella zoster virus
C Gerada, TM Campbell, JJ Kennedy… - Frontiers in …, 2020 - frontiersin.org
Varicella zoster virus (VZV) is the causative agent of chickenpox (varicella) and shingles
(herpes zoster). VZV and other members of the herpesvirus family are distinguished by their …
(herpes zoster). VZV and other members of the herpesvirus family are distinguished by their …
Microbial functional amyloids serve diverse purposes for structure, adhesion and defence
The functional amyloid state of proteins has in recent years garnered much attention for its
role in serving crucial and diverse biological roles. Amyloid is a protein fold characterised by …
role in serving crucial and diverse biological roles. Amyloid is a protein fold characterised by …
Predicting vaccine effectiveness against severe COVID-19 over time and against variants: a meta-analysis
Vaccine protection from symptomatic SARS-CoV-2 infection has been shown to be strongly
correlated with neutralising antibody titres; however, this has not yet been demonstrated for …
correlated with neutralising antibody titres; however, this has not yet been demonstrated for …
Correlates of protection, thresholds of protection, and immunobridging among persons with SARS-CoV-2 infection
Several studies have shown that neutralizing antibody levels correlate with immune
protection from COVID-19 and have estimated the relationship between neutralizing …
protection from COVID-19 and have estimated the relationship between neutralizing …
Analysis of T cell responses during active varicella-zoster virus reactivation in human ganglia
M Steain, JP Sutherland, M Rodriguez… - Journal of …, 2014 - journals.asm.org
Varicella-zoster virus (VZV) is responsible for both varicella (chickenpox) and herpes zoster
(shingles). During varicella, the virus establishes latency within the sensory ganglia and can …
(shingles). During varicella, the virus establishes latency within the sensory ganglia and can …
RHIM-based protein: protein interactions in microbial defence against programmed cell death by necroptosis
MODG Baker, N Shanmugam, CLL Pham… - Seminars in Cell & …, 2020 - Elsevier
The Receptor-interacting protein kinase Homotypic Interaction Motif (RHIM) is an amino acid
sequence that mediates multiple protein: protein interactions in the mammalian programmed …
sequence that mediates multiple protein: protein interactions in the mammalian programmed …
Viral M45 and necroptosis‐associated proteins form heteromeric amyloid assemblies
The murine cytomegalovirus protein M45 protects infected mouse cells from necroptotic
death and, when heterologously expressed, can protect human cells from necroptosis …
death and, when heterologously expressed, can protect human cells from necroptosis …
A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilising immunity against SARS-CoV-2 infection
Global control of COVID-19 requires broadly accessible vaccines that are effective against
SARS-CoV-2 variants. In this report, we exploit the immunostimulatory properties of bacille …
SARS-CoV-2 variants. In this report, we exploit the immunostimulatory properties of bacille …
A meta-analysis of early results to predict vaccine efficacy against Omicron
In the studies to date, the estimated fold-drop in neutralisation titre against Omicron ranges
from 2-to over 20-fold depending on the study and serum tested. Collating data from the first …
from 2-to over 20-fold depending on the study and serum tested. Collating data from the first …