Structural basis for budding by the ESCRT-III factor CHMP3
The vacuolar protein sorting machinery regulates multivesicular body biogenesis and is
selectively recruited by enveloped viruses to support budding. Here we report the crystal …
selectively recruited by enveloped viruses to support budding. Here we report the crystal …
Structural analysis of the adaptor protein ClpS in complex with the N-terminal domain of ClpA
In Escherichia coli, protein degradation is performed by several proteolytic machines,
including ClpAP. Generally, the substrate specificity of these machines is determined by …
including ClpAP. Generally, the substrate specificity of these machines is determined by …
Crystal structure of the UPF2-interacting domain of nonsense-mediated mRNA decay factor UPF1
UPF1 is an essential eukaryotic RNA helicase that plays a key role in various mRNA
degradation pathways, notably nonsense-mediated mRNA decay (NMD). In combination …
degradation pathways, notably nonsense-mediated mRNA decay (NMD). In combination …
Characterization of Photocycle Intermediates in Crystalline Photoactive Yellow Protein†¶
The photocycle in photoactive yellow protein (PYP) crystals was studied by single‐crystal
absorption spectroscopy with experimental setups for low‐temperature and time‐resolved …
absorption spectroscopy with experimental setups for low‐temperature and time‐resolved …
Crystallization and preliminary X-ray analysis of the Escherichia coli adaptor protein ClpS, free and in complex with the N-terminal domain of ClpA
Protein degradation in Escherichia coli is accomplished by a handful of large oligomeric
complexes. In most cases, these proteolytic machines are comprised of a chaperone (eg …
complexes. In most cases, these proteolytic machines are comprised of a chaperone (eg …
Phasing in the presence of radiation damage.
The brightest SR sources create havoc with macromolecular crystals when used at design
specifications. The problem of radiation damage is not only severe in studies involving …
specifications. The problem of radiation damage is not only severe in studies involving …
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