A Recombinant Blood-Stage Malaria Vaccine Reduces Plasmodium falciparum Density and Exerts Selective Pressure on Parasite Populations in a Phase 1-2b Trial …
B Genton, I Betuela, I Felger, F Al-Yaman… - The Journal of …, 2002 - academic.oup.com
The malaria vaccine Combination B comprises recombinant Plasmodium falciparum ring-
infected erythrocyte surface antigen and 2 merozoite surface proteins (MSP1 and MSP2) …
infected erythrocyte surface antigen and 2 merozoite surface proteins (MSP1 and MSP2) …
Plasmodium vivax and mixed infections are associated with severe malaria in children: a prospective cohort study from Papua New Guinea
B Genton, V D'Acremont, L Rare, K Baea… - PLoS …, 2008 - journals.plos.org
Background Severe malaria (SM) is classically associated with Plasmodium falciparum
infection. Little information is available on the contribution of P. vivax to severe disease …
infection. Little information is available on the contribution of P. vivax to severe disease …
Effect of vitamin A supplementation on morbidity due to Plasmodium falciparum in young children in Papua New Guinea: a randomised trial
AH Shankar, B Genton, RD Semba, M Baisor, J Paino… - The Lancet, 1999 - thelancet.com
Background Many individuals at risk of malaria also have micronutrient deficiencies that may
hamper protective immunity. Vitamin A is central to normal immune function, and …
hamper protective immunity. Vitamin A is central to normal immune function, and …
[PDF][PDF] The influence of zinc supplementation on morbidity due to Plasmodium falciparum: a randomized trial in preschool children in Papua New Guinea.
AH Shankar, B Genton, M Baisor, J Paino… - The American journal of …, 2000 - Citeseer
Zinc is crucial for normal immune function and can reduce morbidity from multiple infectious
diseases. To determine the influence of zinc on malaria morbidity we conducted a …
diseases. To determine the influence of zinc on malaria morbidity we conducted a …
The effect of distance from home on attendance at a small rural health centre in Papua New Guinea
Background The willingness of patients in the rural tropics to seek medical care at primary
health care facilities is influenced by the distance they have to travel, but few studies have …
health care facilities is influenced by the distance they have to travel, but few studies have …
Changing patterns of Plasmodium blood-stage infections in the Wosera region of Papua New Guinea monitored by light microscopy and high throughput PCR …
LJ Kasehagen, IVO Mueller… - … American journal of …, 2006 - pmc.ncbi.nlm.nih.gov
In Papua New Guinea (PNG), complex patterns of malaria commonly include single and
mixed infections of Plasmodium falciparum, P. vivax, P. malariae, and P. ovale. Here, we …
mixed infections of Plasmodium falciparum, P. vivax, P. malariae, and P. ovale. Here, we …
Safety and immunogenicity of a three-component blood-stage malaria vaccine in adults living in an endemic area of Papua New Guinea
A Phase I safety and immunogenicity study with a three-component blood-stage malaria
vaccine was conducted in adult male subjects living in an endemic area of Papua New …
vaccine was conducted in adult male subjects living in an endemic area of Papua New …
The epidemiology of malaria in the Wosera area, East Sepik Province, Papua New Guinea, in preparation for vaccine trials. II. Mortality and morbidity
B Genton, F Al-Yaman, HP Beck, J Hii… - Annals of Tropical …, 1995 - Taylor & Francis
Malaria mortality and morbidity were studied in a rural population of 4000 in the Wosera
area, East Sepik Province, Papua New Guinea. Malaria accounted for 4· 9% of the 162 …
area, East Sepik Province, Papua New Guinea. Malaria accounted for 4· 9% of the 162 …
Efficacy of artemether–lumefantrine and dihydroartemisinin–piperaquine for the treatment of uncomplicated malaria in Papua New Guinea
Abstract Background In 2009, the Papua New Guinea (PNG) Department of Health adopted
artemether–lumefantrine (AL) and dihydroartemisinin–piperaquine (DHA-PPQ) as the first …
artemether–lumefantrine (AL) and dihydroartemisinin–piperaquine (DHA-PPQ) as the first …
Quantifying the evolution and impact of antimalarial drug resistance: drug use, spread of resistance, and drug failure over a 12-year period in Papua New Guinea
C Nsanzabana, IM Hastings, J Marfurt… - The Journal of …, 2010 - academic.oup.com
Background. Antimalarial use is a key factor driving drug resistance and reduced treatment
effectiveness in Plasmodium falciparum malaria, but there are few formal, quantitative …
effectiveness in Plasmodium falciparum malaria, but there are few formal, quantitative …