Advances in quantitative PCR technology: 5′ nuclease assays
YS Lie, CJ Petropoulos - Current opinion in biotechnology, 1998 - Elsevier
The development of 5′ nuclease assays represents a significant advance in nucleic acid
quantitation. This approach utilizes the 5′-3′ exonuclease activity of Thermus aquaticus …
quantitation. This approach utilizes the 5′-3′ exonuclease activity of Thermus aquaticus …
Assessing chemokine co-receptor usage in HIV
E Coakley, CJ Petropoulos… - Current opinion in …, 2005 - journals.lww.com
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[HTML][HTML] Multiple early factors anticipate post-acute COVID-19 sequelae
Post-acute sequelae of COVID-19 (PASC) represent an emerging global crisis. However,
quantifiable risk factors for PASC and their biological associations are poorly resolved. We …
quantifiable risk factors for PASC and their biological associations are poorly resolved. We …
A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1
CJ Petropoulos, NT Parkin, KL Limoli… - Antimicrobial agents …, 2000 - journals.asm.org
Although combination antiretroviral therapy has resulted in a considerable improvement in
the treatment of human immunodeficiency virus (HIV) type 1 (HIV-1) infection, the …
the treatment of human immunodeficiency virus (HIV) type 1 (HIV-1) infection, the …
Rapid evolution of the neutralizing antibody response to HIV type 1 infection
DD Richman, T Wrin, SJ Little… - Proceedings of the …, 2003 - pnas.org
A recombinant virus assay was used to characterize in detail neutralizing antibody
responses directed at circulating autologous HIV in plasma. Examining serial plasma …
responses directed at circulating autologous HIV in plasma. Examining serial plasma …
Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies
Broadly neutralizing monoclonal antibodies (MAbs) are potentially important tools in human
immunodeficiency virus type 1 (HIV-1) vaccine design. A few rare MAbs have been …
immunodeficiency virus type 1 (HIV-1) vaccine design. A few rare MAbs have been …
Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia
SG Deeks, T Wrin, T Liegler, R Hoh… - … England Journal of …, 2001 - Mass Medical Soc
Background In many patients with human immunodeficiency virus (HIV) infection, therapy
with potent antiretroviral drugs does not result in complete suppression of HIV replication …
with potent antiretroviral drugs does not result in complete suppression of HIV replication …
Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy
Background. Spontaneous control of human immunodeficiency virus (HIV) infection has
been documented in a minority of HIV-infected individuals. The mechanisms behind this …
been documented in a minority of HIV-infected individuals. The mechanisms behind this …
Chronic viral coinfections differentially affect the likelihood of developing long COVID
MJ Peluso, TM Deveau, SE Munter, D Ryder… - The Journal of clinical …, 2023 - jci.org
BACKGROUND The presence and reactivation of chronic viral infections, such as EBV,
CMV, and HIV, have been proposed as potential contributors to long COVID (LC), but …
CMV, and HIV, have been proposed as potential contributors to long COVID (LC), but …
Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors
SH Hughes, JJ Greenhouse, CJ Petropoulos… - Journal of …, 1987 - journals.asm.org
We have previously described several helper independent vector constructions (S. Hughes
and E. Kosik, Virology 136: 89-99, 1984; J. Sorge and SH Hughes, J. Mol. Appl. Genet. 1 …
and E. Kosik, Virology 136: 89-99, 1984; J. Sorge and SH Hughes, J. Mol. Appl. Genet. 1 …