User profiles for "author:Perera L"
Lalith PereraStaff Scientist, National Institute of Environmental Health Sciences Verified email at niehs.nih.gov Cited by 31945 |
New tricks for modelers from the crystallography toolkit: the particle mesh Ewald algorithm and its use in nucleic acid simulations
The accurate simulation of DNA and RNA has been a goal of theoretical biophysicists for a
number of years. That is, given a high-resolution experimental structure, or perhaps a …
number of years. That is, given a high-resolution experimental structure, or perhaps a …
[HTML][HTML] The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use
PY Perera, JH Lichy, TA Waldmann, LP Perera - Microbes and infection, 2012 - Elsevier
Interleukin-15 (IL-15) is a pleiotropic cytokine with a broad range of biological functions in
many diverse cell types. It plays a major role in the development of inflammatory and …
many diverse cell types. It plays a major role in the development of inflammatory and …
Potential SARS-CoV-2 main protease inhibitors
R Banerjee, L Perera, LMV Tillekeratne - Drug Discovery Today, 2021 - Elsevier
Highlights•The SARS-CoV-2 main protease is a prime drug target.•Coronavirus main
proteases share a structurally conserved substrate-binding region.•The structure and …
proteases share a structurally conserved substrate-binding region.•The structure and …
A smooth particle mesh Ewald method
U Essmann, L Perera, ML Berkowitz… - The Journal of …, 1995 - pubs.aip.org
The previously developed particle mesh Ewald method is reformulated in terms of efficient B‐
spline interpolation of the structure factors. This reformulation allows a natural extension of …
spline interpolation of the structure factors. This reformulation allows a natural extension of …
First observation of the Greisen-Zatsepin-Kuzmin suppression
RU Abbasi, T Abu-Zayyad, M Allen, JF Amman… - Physical review …, 2008 - APS
The High Resolution Fly's Eye (HiRes) experiment has observed the Greisen-Zatsepin-
Kuzmin suppression (called the GZK cutoff) with a statistical significance of five standard …
Kuzmin suppression (called the GZK cutoff) with a statistical significance of five standard …
Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human …
Purpose Interleukin-15 (IL-15) has significant potential in cancer immunotherapy as an
activator of antitumor CD8 T and natural killer (NK) cells. The primary objectives of this trial …
activator of antitumor CD8 T and natural killer (NK) cells. The primary objectives of this trial …
Experimental Evidence for a Light and Broad Scalar Resonance in Decay
EM Aitala, S Amato, JC Anjos, JA Appel, D Ashery… - Physical Review Letters, 2001 - APS
From a sample of 1172±61 D+→ π− π+ π+ decays, we find Γ (D+→ π− π+ π+)/Γ (D+→ K−
π+ π+)= 0.0311±0.0018− 0.0026+ 0.0016. Using a coherent amplitude analysis to fit the …
π+ π+)= 0.0311±0.0018− 0.0026+ 0.0016. Using a coherent amplitude analysis to fit the …
Indications of proton-dominated cosmic-ray composition above 1.6 EeV
RU Abbasi, T Abu-Zayyad, M Al-Seady, M Allen… - Physical Review Letters, 2010 - APS
We report studies of ultrahigh-energy cosmic-ray composition via analysis of depth of air
shower maximum (X max), for air shower events collected by the High-Resolution Fly's Eye …
shower maximum (X max), for air shower events collected by the High-Resolution Fly's Eye …
Molecular dynamics simulation of sodium dodecyl sulfate micelle in water: micellar structural characteristics and counterion distribution
An all-atom 5 nanosecond molecular dynamics simulation of a water-solvated micelle
containing 60 sodium dodecyl sulfate monomers was performed. Structural properties such …
containing 60 sodium dodecyl sulfate monomers was performed. Structural properties such …
Many‐body effects in molecular dynamics simulations of Na+(H2O)n and Cl−(H2O)n clusters
L Perera, ML Berkowitz - The Journal of chemical physics, 1991 - pubs.aip.org
Many‐body effects were examined in a series of molecular dynamics computer simulations
on the ionic aqueous clusters Na+ (H2O) n (n= 4, 5, 6, 14) and Cl−(H2O) n (n= 4, 5, 6, 7, 8 …
on the ionic aqueous clusters Na+ (H2O) n (n= 4, 5, 6, 14) and Cl−(H2O) n (n= 4, 5, 6, 7, 8 …