COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

TM Delorey, CGK Ziegler, G Heimberg, R Normand… - Nature, 2021 - nature.com
COVID-19, which is caused by SARS-CoV-2, can result in acute respiratory distress
syndrome and multiple organ failure,,–, but little is known about its pathophysiology. Here …

[HTML][HTML] A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

TM Delorey, CGK Ziegler, G Heimberg, R Normand… - Biorxiv, 2021 - pmc.ncbi.nlm.nih.gov
The SARS-CoV-2 pandemic has caused over 1 million deaths globally, mostly due to acute
lung injury and acute respiratory distress syndrome, or direct complications resulting in …

Elevated Plasma Levels of Ketone Bodies Are Associated With All‐Cause Mortality and Incidence of Heart Failure in Older Adults: The CHS

S Niezen, MA Connelly, C Hirsch, JR Kizer… - Journal of the …, 2023 - ahajournals.org
Background Chronic disease, such as heart failure, influences cellular metabolism and
shapes circulating metabolites. The relationships between key energy metabolites and …

Coffee consumption is associated with lower liver stiffness: a nationally representative study

S Niezen, M Mehta, ZG Jiang, EB Tapper - Clinical Gastroenterology and …, 2022 - Elsevier
Background & Aims Coffee is associated with a reduced risk of liver disease. This
association is limited by important sources of confounding such as recall bias, healthy user …

Associations between alcohol consumption and hepatic steatosis in the USA

S Niezen, HD Trivedi, KJ Mukamal… - Liver International, 2021 - Wiley Online Library
Despite being widely recognized as a common cause of fatty liver, the exact impact of
alcohol consumption on hepatic steatosis in the general population is elusive. The recent …

A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients

Y Pita-Juarez, D Karagkouni, N Kalavros, JC Melms… - Genome Biology, 2025 - Springer
Background The molecular underpinnings of organ dysfunction in severe COVID-19 and its
potential long-term sequelae are under intense investigation. To shed light on these in the …

Colonoscopy videos on YouTube: Are they a good source of patient education?

D Radadiya, A Gonzalez-Estrada… - Endoscopy …, 2020 - thieme-connect.com
Background and study aims Colonoscopy is an effective tool to prevent colorectal cancer.
Social media has emerged as a source of medical information for patients. YouTube (a …

[PDF][PDF] Prevalence of High Liver Stiffness and a Screening Strategy Using the SODA‐2B Score Among US Adults

S Niezen, EB Tapper, H Trivedi, M Lai… - Hepatology …, 2022 - Wiley Online Library
Cirrhosis, a rising cause of death in the United States, has an extended preclinical phase
characterized by progressive liver fibrosis. Despite the developments in noninvasive fibrosis …

Food Insecurity in Hispanic Populations Is Associated with an Increased Risk of Hepatic Steatosis: A Nationally Representative Study

S Niezen, D Goyes, A Vipani, JD Yang… - Journal of Clinical …, 2024 - mdpi.com
Introduction: The Hispanic population in the US faces a higher risk of nonalcoholic fatty liver
disease (NAFLD). Multiple factors influence this risk, including genetics, environmental …

A randomized study of ceftriaxone for the prevention of infections in hospitalized patients with advanced cirrhosis

Z Fricker, G Jiang, H Patel, A McLaughlin… - Hepatology …, 2024 - journals.lww.com
Background: Infections frequently complicate hospital admission among patients with
cirrhosis and are associated with adverse outcomes. In specific settings, administration of …