User profiles for "author:Milad M"
 | Mohammed R MiladNYU School of Medicine Verified email at nyulangone.org Cited by 25847 |
Fear extinction as a model for translational neuroscience: ten years of progress
MR Milad, GJ Quirk - Annual review of psychology, 2012 - annualreviews.org
The psychology of extinction has been studied for decades. Approximately 10 years ago,
however, there began a concerted effort to understand the neural circuits of extinction of fear …
however, there began a concerted effort to understand the neural circuits of extinction of fear …
Biological studies of post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) is the only major mental disorder for which a cause is
considered to be known: that is, an event that involves threat to the physical integrity of …
considered to be known: that is, an event that involves threat to the physical integrity of …
Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways
Obsessive-compulsive disorder (OCD) affects approximately 2–3% of the population and is
characterized by recurrent intrusive thoughts (obsessions) and repetitive behaviors or …
characterized by recurrent intrusive thoughts (obsessions) and repetitive behaviors or …
Neurons in medial prefrontal cortex signal memory for fear extinction
MR Milad, GJ Quirk - Nature, 2002 - nature.com
Conditioned fear responses to a tone previously paired with a shock diminish if the tone is
repeatedly presented without the shock, a process known as extinction. Since Pavlov it has …
repeatedly presented without the shock, a process known as extinction. Since Pavlov it has …
Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder
BACKGROUND: A clinical characteristic of posttraumatic stress disorder (PTSD) is
persistently elevated fear responses to stimuli associated with the traumatic event. The …
persistently elevated fear responses to stimuli associated with the traumatic event. The …
Recall of fear extinction in humans activates the ventromedial prefrontal cortex and hippocampus in concert
BACKGROUND: Extinction of conditioned fear is thought to form a new safety memory that is
expressed in the context in which the extinction learning took place. Rodent studies …
expressed in the context in which the extinction learning took place. Rodent studies …
Thickness of ventromedial prefrontal cortex in humans is correlated with extinction memory
The ventromedial prefrontal cortex (vmPFC) has been implicated in fear extinction [Phelps,
EA, Delgado, MR, Nearing, KI & Ledoux, JE (2004) Neuron 43, 897-905; Herry, C. & Garcia …
EA, Delgado, MR, Nearing, KI & Ledoux, JE (2004) Neuron 43, 897-905; Herry, C. & Garcia …
Deficits in conditioned fear extinction in obsessive-compulsive disorder and neurobiological changes in the fear circuit
Importance Obsessive-compulsive disorder (OCD) may be characterized by impaired self-
regulation and behavioral inhibition. Elevated fear and anxiety are common characteristics …
regulation and behavioral inhibition. Elevated fear and anxiety are common characteristics …
Fear extinction in rats: implications for human brain imaging and anxiety disorders
Fear extinction is the decrease in conditioned fear responses that normally occurs when a
conditioned stimulus (CS) is repeatedly presented in the absence of the aversive …
conditioned stimulus (CS) is repeatedly presented in the absence of the aversive …
The influence of gonadal hormones on conditioned fear extinction in healthy humans
Recent rodent studies suggest that gonadal hormones influence extinction of conditioned
fear. Here we investigated sex differences in, and the influence of estradiol and …
fear. Here we investigated sex differences in, and the influence of estradiol and …