The role of mechanical forces in tumor growth and therapy

RK Jain, JD Martin… - Annual review of …, 2014 - annualreviews.org
Tumors generate physical forces during growth and progression. These physical forces are
able to compress blood and lymphatic vessels, reducing perfusion rates and creating …

Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges

JD Martin, H Cabral, T Stylianopoulos… - Nature reviews Clinical …, 2020 - nature.com
Multiple nanotherapeutics have been approved for patients with cancer, but their effects on
survival have been modest and, in some examples, less than those of other approved …

Normalizing function of tumor vessels: progress, opportunities, and challenges

JD Martin, G Seano, RK Jain - Annual review of physiology, 2019 - annualreviews.org
Abnormal blood and lymphatic vessels create a hostile tumor microenvironment
characterized by hypoxia, low pH, and elevated interstitial fluid pressure. These …

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Management Group Liefer Laura A. 51 Wetterstrand … - nature, 2007 - nature.com
We report the generation and analysis of functional data from multiple, diverse experiments
performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE …

Factors influencing destination image

A Beerli, JD Martin - Annals of tourism research, 2004 - Elsevier
The aim of this paper is to develop and empirically validate a model which explains the
different factors which form the post-visit image of a destination. Based on a literature review …

Tourists' characteristics and the perceived image of tourist destinations: a quantitative analysis—a case study of Lanzarote, Spain

A Beerli, JD Martı́n - Tourism management, 2004 - Elsevier
This paper is set in the context of tourism marketing, more specifically in the process of
tourist destination image formation. By means of empirical research applied to a …

Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14

RS Ames, HM Sarau, JK Chambers, RN Willette… - Nature, 1999 - nature.com
Abstract Urotensin-II (U-II) is a vasoactive 'somatostatin-like'cyclic peptide which was
originally isolated from fish spinal cords,, and which has recently been cloned from man …

Corporate research and development expenditures and share value

SH Chan, JD Martin, JW Kensinger - Journal of Financial Economics, 1990 - Elsevier
Share-price responses to 95 announcements of increased research and development (R &
D) spending are significantly positive on average, even when the announcement occurs in …

A model of customer loyalty in the retail banking market

A Beerli, JD Martin, A Quintana - European journal of marketing, 2004 - emerald.com
On the basis of empirical research carried out in the retail banking market, this paper
proposes a structural equations model enabling us to reach the conclusions that satisfaction …

Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

VP Chauhan, T Stylianopoulos, JD Martin… - Nano-Enabled …, 2020 - taylorfrancis.com
Unfortunately, the increased hydrodynamic and steric hindrance resulting from the smaller
vessel pores caused by normalization may compromise the advantage gained from …