Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions
Mechanisms underlying severe coronavirus disease 2019 (COVID-19) disease remain
poorly understood. We analyze several thousand plasma proteins longitudinally in 306 …
poorly understood. We analyze several thousand plasma proteins longitudinally in 306 …
SARS-CoV-2 viremia is associated with distinct proteomic pathways and predicts COVID-19 outcomes
BACKGROUND SARS-CoV-2 plasma viremia has been associated with severe disease and
death in COVID-19 in small-scale cohort studies. The mechanisms behind this association …
death in COVID-19 in small-scale cohort studies. The mechanisms behind this association …
Early cross-coronavirus reactive signatures of humoral immunity against COVID-19
The introduction of vaccines has inspired hope in the battle against SARS-CoV-2. However,
the emergence of viral variants, in the absence of potent antivirals, has left the world …
the emergence of viral variants, in the absence of potent antivirals, has left the world …
Alveolar, endothelial, and organ injury marker dynamics in severe COVID-19
DE Leisman, A Mehta, BT Thompson… - American journal of …, 2022 - atsjournals.org
Rationale: Alveolar and endothelial injury may be differentially associated with coronavirus
disease (COVID-19) severity over time. Objectives: To describe alveolar and endothelial …
disease (COVID-19) severity over time. Objectives: To describe alveolar and endothelial …
Longitudinal characterization of circulating neutrophils uncovers phenotypes associated with severity in hospitalized COVID-19 patients
Mechanisms of neutrophil involvement in severe coronavirus disease 2019 (COVID-19)
remain incompletely understood. Here, we collect longitudinal blood samples from 306 …
remain incompletely understood. Here, we collect longitudinal blood samples from 306 …
Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients
COVID-19 has caused over 1 million deaths globally, yet the cellular mechanisms
underlying severe disease remain poorly understood. By analyzing several thousand …
underlying severe disease remain poorly understood. By analyzing several thousand …
[CITATION][C] Longitudinal proteomic analysis of severe COVID-19 reveals survivalassociated signatures, tissue-specific cell death, and cell-cell interactions. Cell Rep …
MR Filbin, A Mehta, AM Schneider, KR Kays, JR Guess… - J. XCRM, 2021
[CITATION][C] Longitudinal proteomic analysis of plasma from patients with severe COVID-19 reveal patient survival-associated signatures, tissue-specific cell death …
[CITATION][C] Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients. bioRxiv [Preprint](2021)
MR Filbin, A Mehta, AM Schneider, KR Kays, JR Guess… - DOI
[CITATION][C] Early cross-coronavirus reactive signatures of humoral immunity against COVID-19. Sci. Immunol. 6, eabj2901
P Kaplonek, C Wang, Y Bartsch, S Fischinger… - 2021