Morphology of alcoholic liver disease

JH Lefkowitch - Clinics in liver disease, 2005 - liver.theclinics.com
Since Mallory's seminal description of the pathology of alcoholic hepatitis [1], the
morphology of alcoholic liver injury has been described in many original investigations and …

Liver biopsy in modern clinical practice: a pediatric point-of-view

N Ovchinsky, RK Moreira, JH Lefkowitch… - Advances in anatomic …, 2012 - journals.lww.com
Liver biopsy remains the foundation of evaluation and management of liver disease in
children, although the role of the liver biopsy is changing with development of alternative …

Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4

DH Dapito, A Mencin, GY Gwak, JP Pradere, MK Jang… - Cancer cell, 2012 - cell.com
Increased translocation of intestinal bacteria is a hallmark of chronic liver disease and
contributes to hepatic inflammation and fibrosis. Here we tested the hypothesis that the …

Liver biopsy assessment in chronic hepatitis

JH Lefkowitch - Archives of medical research, 2007 - Elsevier
Liver biopsy has been a major diagnostic tool in the evaluation of individuals with chronic
hepatitis for many decades and remains the most direct way of visualizing hepatic …

[BOOK][B] Scheuer's Liver Biopsy Interpretation E-Book

JH Lefkowitch - 2020 - books.google.com
Trusted for more than 50 years by pathologists in practice and in training, Scheuer's Liver
Biopsy Interpretation is a well-organized, superbly illustrated guide designed to help solve …

A molecular single-cell lung atlas of lethal COVID-19

JC Melms, J Biermann, H Huang, Y Wang, A Nair… - Nature, 2021 - nature.com
Respiratory failure is the leading cause of death in patients with severe SARS-CoV-2
infection,, but the host response at the lung tissue level is poorly understood. Here we …

[PDF][PDF] Nomenclature of the finer branches of the biliary tree: canals, ductules, and ductular reactions in human livers

TA Roskams, ND Theise, C Balabaud, G Bhagat… - …, 2004 - Wiley Online Library
The work of liver stem cell biologists, largely carried out in rodent models, has now started to
manifest in human investigations and applications. We can now recognize complex …

[PDF][PDF] The long‐term pathological evolution of chronic hepatitis C

M Yano, H Kumada, M Kage, K Ikeda… - …, 1996 - Wiley Online Library
Most patients infected with hepatitis C virus (HCV) develop chronic hepatitis. Unfortunately,
the pathological evolution of this disease over time is not completely understood. We studied …

[PDF][PDF] JNK1 but not JNK2 promotes the development of steatohepatitis in mice

JM Schattenberg, R Singh, Y Wang, JH Lefkowitch… - …, 2006 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis and varying
degrees of necroinflammation. Although chronic oxidative stress, inflammatory cytokines …

Hepatocyte TAZ/WWTR1 promotes inflammation and fibrosis in nonalcoholic steatohepatitis

X Wang, ZE Zheng, JM Caviglia, KE Corey, TM Herfel… - Cell metabolism, 2016 - cell.com
Nonalcoholic steatohepatitis (NASH) is a leading cause of liver disease worldwide.
However, the molecular basis of how benign steatosis progresses to NASH is incompletely …