Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): a multicentre, double-blind, randomised, phase 2b …
A Llanos-Cuentas, MV Lacerda, R Rueangweerayut… - The Lancet, 2014 - thelancet.com
Background Clinical effectiveness of previous regimens to treat Plasmodium vivax infection
have been hampered by compliance. We aimed to assess the dose–response, safety, and …
have been hampered by compliance. We aimed to assess the dose–response, safety, and …
[HTML][HTML] Severe plasmodium vivax malaria, Brazilian Amazon
MA Alexandre, CO Ferreira, AM Siqueira… - Emerging infectious …, 2010 - ncbi.nlm.nih.gov
We describe a case series of 17 patients hospitalized in Manaus (western Brazilian
Amazon) with PCR-confirmed Plasmodium vivax infection who were treated with …
Amazon) with PCR-confirmed Plasmodium vivax infection who were treated with …
Pathological methods applied to the investigation of causes of death in developing countries: minimally invasive autopsy approach
P Castillo, E Ussene, MR Ismail, D Jordao, L Lovane… - PloS one, 2015 - journals.plos.org
Background and Aims Complete diagnostic autopsies (CDA) remain the gold standard in the
determination of cause of death (CoD). However, performing CDAs in developing countries …
determination of cause of death (CoD). However, performing CDAs in developing countries …
Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile
B Baro, K Deroost, T Raiol, M Brito, ACG Almeida… - 2017 - journals.plos.org
Plasmodium vivax is the most widely distributed human malaria parasite and responsible for
large amounts of disease and burden [1]. The presence of P. vivax in the bone marrow was …
large amounts of disease and burden [1]. The presence of P. vivax in the bone marrow was …
Spread of Gamma (P. 1) sub-lineages carrying Spike mutations close to the furin cleavage site and deletions in the N-terminal domain drives ongoing transmission of …
FG Naveca, V Nascimento, V Souza… - Microbiology …, 2022 - Am Soc Microbiol
The Amazonas was one of the most heavily affected Brazilian states by the COVID-19
epidemic. Despite a large number of infected people, particularly during the second wave …
epidemic. Despite a large number of infected people, particularly during the second wave …
Plasmodium vivax: Induction of CD4+CD25+FoxP3+ Regulatory T Cells during Infection Are Directly Associated with Level of Circulating Parasites
Circulation CD4+ CD25+ FoxP3+ regulatory T cells (Tregs) have been associated with the
delicate balancing between control of overwhelming acute malaria infection and prevention …
delicate balancing between control of overwhelming acute malaria infection and prevention …
Bacterial sexually transmitted infections among men who have sex with men and transgender women using oral pre-exposure prophylaxis in Latin America (ImPrEP) …
MST Silva, TS Torres, C Coutinho, RI Moreira… - The Lancet …, 2024 - thelancet.com
Background The global burden of sexually transmitted infections (STIs) poses a challenge in
the context of HIV pre-exposure prophylaxis (PrEP) programmes. We aimed to explore …
the context of HIV pre-exposure prophylaxis (PrEP) programmes. We aimed to explore …
Rosetting in Plasmodium vivax: A Cytoadhesion Phenotype Associated with Anaemia
A Marín-Menéndez, A Bardají… - PLoS neglected …, 2013 - journals.plos.org
Background Plasmodium vivax can potentially lead to life-threatening episodes but the
mechanisms underlying severe disease remain poorly defined. Cytoadhesion of infected …
mechanisms underlying severe disease remain poorly defined. Cytoadhesion of infected …
Identification of a Highly Antigenic Linear B Cell Epitope within Plasmodium vivax Apical Membrane Antigen 1 (AMA-1)
Apical membrane antigen 1 (AMA-1) is considered to be a major candidate antigen for a
malaria vaccine. Previous immunoepidemiological studies of naturally acquired immunity to …
malaria vaccine. Previous immunoepidemiological studies of naturally acquired immunity to …
Glucose-6-phosphate dehydrogenase deficient variants are associated with reduced susceptibility to malaria in the Brazilian Amazon
Background Glucose-6-phosphate dehydrogenase deficiency (G6PDd) has been shown to
protect against malaria infection and severe manifestations in African and Asia, but there is a …
protect against malaria infection and severe manifestations in African and Asia, but there is a …