User profiles for "author:Krammer F"

Florian Krammer

Icahn School of Medicine at Mount Sinai
Verified email at mssm.edu
Cited by 60819

SARS-CoV-2 vaccines in development

F Krammer - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in late
2019 in China and is the causative agent of the coronavirus disease 2019 (COVID-19) …

The human antibody response to influenza A virus infection and vaccination

F Krammer - Nature Reviews Immunology, 2019 - nature.com
The adaptive immune response to influenza virus infection is multifaceted and complex,
involving antibody and cellular responses at both systemic and mucosal levels. Immune …

Advances in the development of influenza virus vaccines

F Krammer, P Palese - Nature reviews Drug discovery, 2015 - nature.com
Influenza virus infections are a major public health concern and cause significant morbidity
and mortality worldwide. Current influenza virus vaccines are an effective countermeasure …

A serological assay to detect SARS-CoV-2 seroconversion in humans

F Amanat, D Stadlbauer, S Strohmeier, THO Nguyen… - Nature medicine, 2020 - nature.com
Here, we describe a serological enzyme-linked immunosorbent assay for the screening and
identification of human SARS-CoV-2 seroconverters. This assay does not require the …

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez… - Science, 2020 - science.org
INTRODUCTION Clinical outcomes of human severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus …

[HTML][HTML] Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals

A Grifoni, D Weiskopf, SI Ramirez, J Mateus, JM Dan… - Cell, 2020 - cell.com
Understanding adaptive immunity to SARS-CoV-2 is important for vaccine development,
interpreting coronavirus disease 2019 (COVID-19) pathogenesis, and calibration of …

[HTML][HTML] SARS-CoV-2 vaccines: status report

F Amanat, F Krammer - Immunity, 2020 - cell.com
SARS-CoV-2, the causal agent of COVID-19, first emerged in late 2019 in China. It has since
infected more than 870,000 individuals and caused more than 43,000 deaths globally. Here …

NAction! How can neuraminidase-based immunity contribute to better influenza virus vaccines?

F Krammer, RAM Fouchier, MC Eichelberger… - MBio, 2018 - journals.asm.org
Neuraminidase is one of the two surface glycoproteins of influenza A and B viruses. It has
enzymatic activity that cleaves terminal sialic acid from glycans, and that activity is essential …

Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron

JM Carreño, H Alshammary, J Tcheou, G Singh… - Nature, 2022 - nature.com
Abstract The Omicron (B. 1.1. 529) variant of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) was initially identified in November 2021 in South Africa and Botswana, as …

[HTML][HTML] Immunology of COVID-19: current state of the science

N Vabret, GJ Britton, C Gruber, S Hegde, J Kim… - Immunity, 2020 - cell.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting …