Serologic markers in inflammatory bowel disease

X Bossuyt - Clinical chemistry, 2006 - academic.oup.com
Inflammatory bowel disease (IBD) is an enduring disease involving mostly young people,
with symptoms of bloody diarrhea and abdominal cramps. Several antibodies have been …

Revised 2017 international consensus on testing of ANCAs in granulomatosis with polyangiitis and microscopic polyangiitis

X Bossuyt, JW Cohen Tervaert, Y Arimura… - Nature Reviews …, 2017 - nature.com
Anti-neutrophil cytoplasmic antibodies (ANCAs) are valuable laboratory markers used for
the diagnosis of well-defined types of small-vessel vasculitis, including granulomatosis with …

Current concepts and future directions for the assessment of autoantibodies to cellular antigens referred to as anti‐nuclear antibodies

M Mahler, PL Meroni, X Bossuyt… - Journal of immunology …, 2014 - Wiley Online Library
The detection of autoantibodies that target intracellular antigens, commonly termed anti‐
nuclear antibodies (ANA), is a serological hallmark in the diagnosis of systemic autoimmune …

International recommendations for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies

N Agmon-Levin, J Damoiseaux, C Kallenberg… - Annals of the rheumatic …, 2014 - Elsevier
Anti-nuclear antibodies (ANA) are fundamental for the diagnosis of autoimmune diseases,
and have been determined by indirect immunofluorescence assay (IIFA) for decades. As the …

Selective predisposition to bacterial infections in IRAK-4–deficient children: IRAK-4–dependent TLRs are otherwise redundant in protective immunity

CL Ku, H Von Bernuth, C Picard, SY Zhang… - The Journal of …, 2007 - rupress.org
Human interleukin (IL) 1 receptor–associated kinase 4 (IRAK-4) deficiency is a recently
discovered primary immunodeficiency that impairs Toll/IL-1R immunity, except for the Toll …

A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic …

P Quartier, F Allantaz, R Cimaz, P Pillet… - Annals of the …, 2011 - ard.bmj.com
Objectives To assess the efficacy of the interleukin 1 receptor antagonist anakinra in
systemic-onset juvenile idiopathic arthritis (SJIA). Methods A multicentre, randomised …

Diagnostic Value of Anti-Saccharomyces Cerevisiaeand Antineutrophil Cytoplasmic Autoantibodies in Inflammatory Bowel Disease

M Peeters, S Joossens, S Vermeire… - Official journal of the …, 2001 - journals.lww.com
OBJECTIVES: Correct diagnosis of inflammatory bowel disease (IBD), especially the
differentiation between Crohn's disease (CD) and ulcerative colitis (UC), is highly important …

Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency

C Picard, H Von Bernuth, P Ghandil, M Chrabieh… - Medicine, 2010 - journals.lww.com
Autosomal recessive interleukin-1 receptor-associated kinase (IRAK)-4 and myeloid
differentiation factor (MyD) 88 deficiencies impair Toll-like receptor (TLR)-and interleukin-1 …

Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency

B Boisson, E Laplantine, C Prando, S Giliani… - Nature …, 2012 - nature.com
We report the clinical description and molecular dissection of a new fatal human inherited
disorder characterized by chronic autoinflammation, invasive bacterial infections and …

The value of serologic markers in indeterminate colitis: a prospective follow-up study

S Joossens, W Reinisch, S Vermeire, B Sendid… - Gastroenterology, 2002 - Elsevier
BACKGROUND & AIMS: In the absence of pathognomonic markers for Crohn's disease
(CD) and ulcerative colitis (UC), the diagnosis of inflammatory bowel disease depends on a …