Extensive unexplored human microbiome diversity revealed by over 150,000 genomes from metagenomes spanning age, geography, and lifestyle
The body-wide human microbiome plays a role in health, but its full diversity remains
uncharacterized, particularly outside of the gut and in international populations. We …
uncharacterized, particularly outside of the gut and in international populations. We …
Mother-to-infant microbial transmission from different body sites shapes the developing infant gut microbiome
The acquisition and development of the infant microbiome are key to establishing a healthy
host-microbiome symbiosis. The maternal microbial reservoir is thought to play a crucial role …
host-microbiome symbiosis. The maternal microbial reservoir is thought to play a crucial role …
Fecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial
Fecal microbiota transplantation (FMT) represents a potential strategy to overcome
resistance to immune checkpoint inhibitors in patients with refractory melanoma; however …
resistance to immune checkpoint inhibitors in patients with refractory melanoma; however …
The person-to-person transmission landscape of the gut and oral microbiomes
The human microbiome is an integral component of the human body and a co-determinant
of several health conditions,. However, the extent to which interpersonal relations shape the …
of several health conditions,. However, the extent to which interpersonal relations shape the …
Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation
Several studies have investigated links between the gut microbiome and colorectal cancer
(CRC), but questions remain about the replicability of biomarkers across cohorts and …
(CRC), but questions remain about the replicability of biomarkers across cohorts and …
Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma
The composition of the gut microbiome has been associated with clinical responses to
immune checkpoint inhibitor (ICI) treatment, but there is limited consensus on the specific …
immune checkpoint inhibitor (ICI) treatment, but there is limited consensus on the specific …
Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseases
Fecal microbiota transplantation (FMT) is highly effective against recurrent Clostridioides
difficile infection and is considered a promising treatment for other microbiome-related …
difficile infection and is considered a promising treatment for other microbiome-related …
The Prevotella copri complex comprises four distinct clades underrepresented in westernized populations
Prevotella copri is a common human gut microbe that has been both positively and
negatively associated with host health. In a cross-continent meta-analysis exploiting> 6,500 …
negatively associated with host health. In a cross-continent meta-analysis exploiting> 6,500 …
Studying vertical microbiome transmission from mothers to infants by strain-level metagenomic profiling
The gut microbiome becomes shaped in the first days of life and continues to increase its
diversity during the first months. Links between the configuration of the infant gut microbiome …
diversity during the first months. Links between the configuration of the infant gut microbiome …
Maternal inheritance of bifidobacterial communities and bifidophages in infants through vertical transmission
Background The correct establishment of the human gut microbiota represents a crucial
development that commences at birth. Different hypotheses propose that the infant gut …
development that commences at birth. Different hypotheses propose that the infant gut …