The term “macrolide” was originally proposed by RB Woodward in 1957 as an abbreviation
of macrolactone glycoside antibiotics, a class of natural products composed of macrocyclic …

A Symposium entitled" Classification of Large-Scale Flow-Transverse Bedforms" was
convened at the 1987 Mid-Year Meeting of SEPM in Austin, Texas with the purpose of …

ABSTRACT The Scott and Yana outwash fans on the northeastern Gulf of Alaska exhibit a
succession of facies from glacier terminus to tidewater that are each characterized by …

The structures of complex polyketide natural products, such as erythromycin, are
programmed by multifunctional polyketide synthases (PKSs) that contain modular …

Many drugs and drug candidates are suboptimal because of short duration of action. For
example, peptides and proteins often have serum half-lives of only minutes to hours. One …

Michael-addition of a thiol to a maleimide is commonly used for bioconjugation of drugs to
macromolecules. Indeed, both current FDA-approved antibody–drug conjugates …

Excavation in the previously little-explored western portion of Olduvai Gorge indicates that
hominid land use of the eastern paleobasin extended at least episodically to the west. Finds …

A putative catalytic triad consisting of tyrosine, serine, and lysine residues was identified in
the ketoreductase (KR) domains of modular polyketide synthases (PKSs) based on …

Rhythmic Sedimentation in Glacial Lake Hitchcock, Massachusetts-Connecticut Page 1
RHYTHMIC SEDIMENTATION IN GLACIAL LAKE HITCHCOCK MASSACHUSETTS …

Thirteen runs were made in a small recirculating flume to simulate the deposition of the
climbing‐ripple sequences commonly present in fine‐grained facies of fluvial and deltaic …