User profiles for "author:Østergaard L"
Cerebral small vessel disease: capillary pathways to stroke and cognitive decline
L Østergaard, TS Engedal, F Moreton… - Journal of Cerebral …, 2016 - journals.sagepub.com
Cerebral small vessel disease (SVD) gives rise to one in five strokes worldwide and
constitutes a major source of cognitive decline in the elderly. SVD is known to occur in …
constitutes a major source of cognitive decline in the elderly. SVD is known to occur in …
SARS CoV‐2 related microvascular damage and symptoms during and after COVID‐19: Consequences of capillary transit‐time changes, tissue hypoxia and …
L Østergaard - Physiological reports, 2021 - Wiley Online Library
Abstract Corona virus disease 2019 (COVID‐19) causes symptoms from multiple organs
after infection by severe acute respiratory syndrome corona virus 2 (SARS CoV‐2). They …
after infection by severe acute respiratory syndrome corona virus 2 (SARS CoV‐2). They …
The capillary dysfunction hypothesis of Alzheimer's disease
L Østergaard, R Aamand, E Gutiérrez-Jiménez… - Neurobiology of …, 2013 - Elsevier
It is widely accepted that hypoperfusion and changes in capillary morphology are involved in
the etiopathogenesis of Alzheimer's disease (AD). This is difficult to reconcile with the …
the etiopathogenesis of Alzheimer's disease (AD). This is difficult to reconcile with the …
High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part I: Mathematical approach and statistical analysis
L Østergaard, RM Weisskoff, DA Chesler… - Magnetic resonance …, 1996 - Wiley Online Library
The authors review the theoretical basis of determination of cerebral blood flow (CBF) using
dynamic measurements of nondiffusible contrast agents, and demonstrate how parametric …
dynamic measurements of nondiffusible contrast agents, and demonstrate how parametric …
Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant …
RR Bahadoer, EA Dijkstra, B van Etten… - The Lancet …, 2021 - thelancet.com
Background Systemic relapses remain a major problem in locally advanced rectal cancer.
Using short-course radiotherapy followed by chemotherapy and delayed surgery, the Rectal …
Using short-course radiotherapy followed by chemotherapy and delayed surgery, the Rectal …
The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo
OS Søgaard, ME Graversen, S Leth, R Olesen… - PLoS …, 2015 - journals.plos.org
Pharmacologically-induced activation of replication competent proviruses from latency in the
presence of antiretroviral treatment (ART) has been proposed as a step towards curing HIV …
presence of antiretroviral treatment (ART) has been proposed as a step towards curing HIV …
High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II: Experimental comparison and preliminary results
This report evaluates several methods to map relative cerebral blood flow (rCBF) by
applying both parametric and non‐parametric techniques to deconvolve high resolution …
applying both parametric and non‐parametric techniques to deconvolve high resolution …
Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group …
TA Rasmussen, M Tolstrup, CR Brinkmann… - The lancet HIV, 2014 - thelancet.com
Background Activating the expression of latent virus is an approach that might form part of
an HIV cure. We assessed the ability of the histone deacetylase inhibitor panobinostat to …
an HIV cure. We assessed the ability of the histone deacetylase inhibitor panobinostat to …
Maternal infection requiring hospitalization during pregnancy and autism spectrum disorders
HÓ Atladóttir, P Thorsen, L Østergaard… - Journal of autism and …, 2010 - Springer
Exposure to prenatal infection has been suggested to cause deficiencies in fetal
neurodevelopment. In this study we included all children born in Denmark from 1980 …
neurodevelopment. In this study we included all children born in Denmark from 1980 …
BEaST: brain extraction based on nonlocal segmentation technique
Brain extraction is an important step in the analysis of brain images. The variability in brain
morphology and the difference in intensity characteristics due to imaging sequences make …
morphology and the difference in intensity characteristics due to imaging sequences make …