User profiles for "author:Østergaard L"

Leif Østergaard - Verified email at cfin.au.dk - Cited by 28201
Lasse Riis Østergaard - Verified email at hst.aau.dk - Cited by 1747

Cerebral small vessel disease: capillary pathways to stroke and cognitive decline

L Østergaard, TS Engedal, F Moreton… - Journal of Cerebral …, 2016 - journals.sagepub.com
Cerebral small vessel disease (SVD) gives rise to one in five strokes worldwide and
constitutes a major source of cognitive decline in the elderly. SVD is known to occur in …

SARS CoV‐2 related microvascular damage and symptoms during and after COVID‐19: Consequences of capillary transit‐time changes, tissue hypoxia and …

L Østergaard - Physiological reports, 2021 - Wiley Online Library
Abstract Corona virus disease 2019 (COVID‐19) causes symptoms from multiple organs
after infection by severe acute respiratory syndrome corona virus 2 (SARS CoV‐2). They …

The capillary dysfunction hypothesis of Alzheimer's disease

L Østergaard, R Aamand, E Gutiérrez-Jiménez… - Neurobiology of …, 2013 - Elsevier
It is widely accepted that hypoperfusion and changes in capillary morphology are involved in
the etiopathogenesis of Alzheimer's disease (AD). This is difficult to reconcile with the …

High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part I: Mathematical approach and statistical analysis

L Østergaard, RM Weisskoff, DA Chesler… - Magnetic resonance …, 1996 - Wiley Online Library
The authors review the theoretical basis of determination of cerebral blood flow (CBF) using
dynamic measurements of nondiffusible contrast agents, and demonstrate how parametric …

Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant …

RR Bahadoer, EA Dijkstra, B van Etten… - The Lancet …, 2021 - thelancet.com
Background Systemic relapses remain a major problem in locally advanced rectal cancer.
Using short-course radiotherapy followed by chemotherapy and delayed surgery, the Rectal …

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo

OS Søgaard, ME Graversen, S Leth, R Olesen… - PLoS …, 2015 - journals.plos.org
Pharmacologically-induced activation of replication competent proviruses from latency in the
presence of antiretroviral treatment (ART) has been proposed as a step towards curing HIV …

High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II: Experimental comparison and preliminary results

L Østergaard, AG Sorensen, KK Kwong… - Magnetic resonance …, 1996 - Wiley Online Library
This report evaluates several methods to map relative cerebral blood flow (rCBF) by
applying both parametric and non‐parametric techniques to deconvolve high resolution …

Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group …

TA Rasmussen, M Tolstrup, CR Brinkmann… - The lancet HIV, 2014 - thelancet.com
Background Activating the expression of latent virus is an approach that might form part of
an HIV cure. We assessed the ability of the histone deacetylase inhibitor panobinostat to …

Maternal infection requiring hospitalization during pregnancy and autism spectrum disorders

HÓ Atladóttir, P Thorsen, L Østergaard… - Journal of autism and …, 2010 - Springer
Exposure to prenatal infection has been suggested to cause deficiencies in fetal
neurodevelopment. In this study we included all children born in Denmark from 1980 …

BEaST: brain extraction based on nonlocal segmentation technique

SF Eskildsen, P Coupé, V Fonov, JV Manjón, KK Leung… - NeuroImage, 2012 - Elsevier
Brain extraction is an important step in the analysis of brain images. The variability in brain
morphology and the difference in intensity characteristics due to imaging sequences make …