Ki-67 protein has been widely used as a proliferation marker for human tumor cells for
decades. In recent studies, multiple molecular functions of this large protein have become …

The advent of RNA-sequencing (RNA-Seq) technologies has markedly improved our
knowledge and expanded the compendium of small non-coding RNAs, most of which derive …

Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignant
cancers, and patients with HNSCC possess early metastases and poor prognosis …

The rates of ribosome production by a nucleolus and of protein biosynthesis by ribosomes
are tightly correlated with the rate of cell growth and proliferation. All these processes must …

Proper protein arginine methylation by protein arginine methyltransferase 1 (PRMT1) is
critical for maintaining cellular health, while dysregulation is often associated with disease …

Latest statistics showed that the morbidity and mortality of colon adenocarcinoma (COAD)
ranked fourth and fifth, respectively, around the world. COAD was a heterogeneous disease …

Cell invasion through basement membrane (BM) barriers is important in development,
immune function and cancer progression. As invasion through BM is often stochastic …

Aurora A–dependent NF-κB signaling portends poor prognosis in acute myeloid leukemia
(AML) and other cancers, but the functional basis underlying this association is unclear …

Nucleolar protein interacting with the FHA domain of pKi-67 (NIFK) is a Ki-67-interacting
protein. However, its precise function in cancer remains largely uninvestigated. Here we …

The generation of new ribosomes is a coordinated process essential to sustain cell growth.
As such, it is tightly regulated according to cell needs. As cancer cells require intense protein …