The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the …

Advances in extracorporeal membrane oxygenation (ECMO) management have helped to
reduce complications compared with its inception but they remain high. The principal causes …

Background This guideline addresses the management of patients who are receiving
anticoagulant or antiplatelet therapy and require an elective surgery or procedure. Methods …

Background The American College of Chest Physicians Clinical Practice Guideline on the
Perioperative Management of Antithrombotic Therapy addresses 43 Patients-Interventions …

The PFA-100 (platelet function analyzer) is a relatively new tool for the investigation of
primary hemostasis. This article reviews the history of the PFA-100 and details its clinical …

Background: Infusion of artificial colloids such as hydroxyethyl starch (HES) induces
coagulopathy to a greater extent than simple dilution. Several studies have suggested that …

The advent of modern instrumentation, with associated improvements in test reliability,
together with appropriate internal quality control and external quality assurance measures …

Background: Quantitative bleeding assessment tools (BATs) have been used to describe the
severity of the bleeding phenotype in patients with von Willebrand disease. Objectives: To …

Patient Blood Management (PBM) is a holistic approach to the management of blood as a
resource for each, single patient; it is a multimodal strategy that is implemented through the …

Standardizing the risk of bleeding remains an important clinical goal, and ideally should take
into account coagulation factors, platelet functionality, and vascular integrity issues. One …