Regional specialization within the mammalian respiratory immune system

DPH van Konijnenburg, PA Nigrovic, I Zanoni - Trends in Immunology, 2024 - cell.com
The respiratory tract is exposed to infection from inhaled pathogens, including viruses,
bacteria, and fungi. So far, a comprehensive assessment that integrates common and …

Mechanisms of radiation‐induced tissue damage and response

L Zhou, J Zhu, Y Liu, PK Zhou, Y Gu - MedComm, 2024 - Wiley Online Library
Radiation‐induced tissue injury (RITI) is the most common complication in clinical tumor
radiotherapy. Due to the heterogeneity in the response of different tissues to radiation (IR) …

Variants and vaccines impact nasal immunity over three waves of SARS-CoV-2

JML Walsh, VN Miao, AH Owings, Y Tang… - Nature …, 2025 - nature.com
Viral variant and host vaccination status impact infection with severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), yet how these factors shift cellular responses in the …

Deconstructing inflammatory memory across tissue setpoints using cell circuit motifs

AC Kwong, J Ordovas-Montanes - Journal of Allergy and Clinical …, 2024 - Elsevier
Tissue ecosystems are cellular communities that maintain setpoints through a network of
intercellular interactions. We position health and chronic inflammatory disease as alternative …

Nasal tissue-resident memory CD4+ T cells persist after influenza A virus infection and provide heterosubtypic protection

NR Mathew, R Gailleton, L Scharf, K Schön… - bioRxiv, 2024 - biorxiv.org
CD4 tissue-resident memory T (CD4 TRM) cells are crucial adaptive immune components
involved in preventing influenza A virus (IAV) infection. Despite their importance, their …