Dysregulated immune responses in SARS-CoV-2-infected patients: a comprehensive overview

I Kudryavtsev, A Rubinstein, A Golovkin, O Kalinina… - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in
humans more than two years ago and caused an unprecedented socio-economic burden on …

[HTML][HTML] Immunohematologic Biomarkers in COVID-19: Insights into Pathogenesis, Prognosis, and Prevention

DR Sweet, ML Freeman, DA Zidar - Pathogens and Immunity, 2023 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) has had profound effects on the health of
individuals and on healthcare systems worldwide. While healthcare workers on the …

An early Th1 response is a key factor for a favorable COVID-19 evolution

FJ Gil-Etayo, S Garcinuño, A Utrero-Rico… - Biomedicines, 2022 - mdpi.com
The Th1/Th2 balance plays a crucial role in the progression of different pathologies and is a
determining factor in the evolution of infectious diseases. This work has aimed to evaluate …

Immune dysfunction prior to and during vaccination in multiple myeloma: a case study based on COVID-19

E Martín-Sánchez, LE Tamariz-Amador… - Blood Cancer …, 2024 - nature.com
Infection is the leading cause of death in multiple myeloma (MM). However, the cellular
composition associated with immune dysfunction is not defined. We analyzed immune …

Early inflammatory profiles predict maximal disease severity in COVID-19: An unsupervised cluster analysis

G Kenny, G Saini, CM Gaillard, R Negi, D Alalwan… - Heliyon, 2024 - cell.com
Background The inflammatory changes that underlie the heterogeneous presentations of
COVID-19 remain incompletely understood. In this study we aimed to identify inflammatory …

In silico analysis of the aggregation propensity of the SARS-CoV-2 proteome: Insight into possible cellular pathologies

M Flores-León, DF Lázaro, L Shvachiy, A Krisko… - … et Biophysica Acta (BBA …, 2021 - Elsevier
The SARS-CoV-2 virus causes the coronavirus disease 19 emerged in 2020. The pandemic
triggered a turmoil in public health and is having a tremendous social and economic impact …

COVID‐19: Using high‐throughput flow cytometry to dissect clinical heterogeneity

I del Molino del Barrio, TS Hayday, AG Laing… - Cytometry Part …, 2023 - Wiley Online Library
Here we consider how high‐content flow cytometric methodology at appropriate scale and
throughput rapidly provided meaningful biological data in our recent studies of COVID‐19 …

Reduced absolute count of monocytes in patients carrying hematological neoplasms and SARS-CoV2 infection

A Romano, C Cerchione, C Conticello, S Filetti, A Bulla… - Cancers, 2022 - mdpi.com
Simple Summary In hematological neoplasms associated with COVID-19, immunological
dysfunction, including reduced count of non-classical monocytes, has been suggested as a …

Whole blood transcriptome signature predicts severe forms of COVID-19: Results from the COVIDeF cohort study

R Armignacco, N Carlier, A Jouinot, MF Birtolo… - Functional & Integrative …, 2024 - Springer
COVID-19 is associated with heterogeneous outcome. Early identification of a severe
progression of the disease is essential to properly manage the patients and improve their …

Disease monitoring in multiple myeloma

J Hillengass, T Martin, N Puig, B Paiva… - … Myeloma and Leukemia, 2023 - Elsevier
The outcome for multiple myeloma (MM) patients has significantly improved in the last two
decades, mainly due to the use of novel drugs with a singular mechanism of action …