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Dynamically learned PSO based neighborhood influenced fuzzy c-means for pre-treatment and post-treatment organ segmentation from CT images

Comput Methods Programs Biomed. 2021 Apr:202:105971. doi: 10.1016/j.cmpb.2021.105971. Epub 2021 Feb 4.

Abstract

Background and objective: The accurate segmentation of pre-treatment and post-treatment organs is always perceived as a challenging task in medical image analysis field. Especially, in those situations where the amount of data set is limited, the researchers are compelled to design unsupervised model for segmentation. In this paper, we propose a novel dynamically learned particle swarm optimization based neighborhood influenced fuzzy c-means (DLPSO-NIFCM) clustering (unsupervised learning model) for solving pre-treatment and post-treatment organs segmentation problems. The proposed segmentation technique has been successfully applied to segment the liver parts from the Computed Tomography (CT) images of abdomen and also the lung parenchyma from the lungs CT images.

Methodology: In the proposed method, we formulate a primary convex objective function by considering the membership value of a pixel as well as the membership of its other neighboring pixels. Then we apply a new algebraic transformation on the primary objective function to design a new and more suitable objective function without losing convexity of the primary objective function. This new objective function is compatible for hybridization with any heuristic search technique in true sense. In this work, we propose a dynamically learned PSO to obtain the initial cluster centroids from the final objective function. Finally, we use a graph-based isolation mechanism for refining the segmentation results.

Results and conclusion: This hybrid method, along with the restructured single variable objective function of the distance, leads to accurate clustering results with relatively lesser converging time as compared to the state-of-the-art methods. The segmentation results, obtained through several experiments with real CT images, are encouraging. The numerical values of different performance metrics obtained over the same data set confirm that the proposed algorithm performs better with respect to the state-of-the-art methods. Hence, we may consider the proposed method as a promising tool for clustering and CT image segmentation in a Computer Aided Diagnostic (CAD) system.

Keywords: Agent based optimization; Fuzzy clustering; Image segmentation.

MeSH terms

  • Algorithms*
  • Brain
  • Cluster Analysis
  • Fuzzy Logic*
  • Image Processing, Computer-Assisted
  • Tomography, X-Ray Computed