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Community-Based Antiretroviral Therapy (ART) Delivery for Female Sex Workers in Tanzania: 6-Month ART Initiation and Adherence

AIDS Behav. 2019 Sep;23(Suppl 2):142-152. doi: 10.1007/s10461-019-02549-x.

Abstract

We conducted an implementation science study of a community-based ART distribution program for HIV-positive female sex workers (FSW) whereby clients received ART services through community-based mobile and home-based platforms. We compared 6-month treatment-related outcomes in the community-based ART arm (N = 256) to the standard facility-based ART delivery arm (N = 253). Those in the intervention arm were more likely to have initiated ART (100.0% vs. 71.5%; p = 0.04), be currently taking ART at the 6-month visit (100.0% vs. 95.0%; p < 0.01), and less likely to have stopped taking ART for more than 30 days continuously (0.9% vs. 5.7%; p = 0.008) or feel high levels of internalized stigma (26.6% vs. 39.9%; p = 0.001). In the adjusted regression model, internalized stigma (adjusted OR [aOR]: 0.5; 95% CI 0.28-0.83) and receiving community-based ART (aOR: 208.6; 95% CI 12.5-3479.0) were significantly associated with ART initiation. Community-based ART distribution model can improve linkage to and adherence to ART over standard facility-based ART programs for FSWs.

Keywords: ART initiation; Adherence; Community-based ART; Female sex workers (FSW); Tanzania.

MeSH terms

  • Adolescent
  • Adult
  • Antiretroviral Therapy, Highly Active / psychology*
  • Antiretroviral Therapy, Highly Active / statistics & numerical data
  • Community Health Services / organization & administration*
  • Delivery of Health Care / methods*
  • Female
  • Follow-Up Studies
  • HIV Infections / diagnosis
  • HIV Infections / drug therapy*
  • HIV Infections / epidemiology
  • HIV Infections / virology*
  • Humans
  • Medication Adherence*
  • Patient Acceptance of Health Care
  • Prospective Studies
  • Sex Work
  • Sex Workers / psychology
  • Sex Workers / statistics & numerical data*
  • Social Stigma
  • Tanzania / epidemiology
  • Treatment Outcome
  • Young Adult