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The Expanding and Unexpected Functions of Mitochondria Contact Sites

Trends Cell Biol. 2019 Jul;29(7):580-590. doi: 10.1016/j.tcb.2019.02.009. Epub 2019 Mar 28.

Abstract

Mitochondria make functionally relevant contacts with most, if not all, other organelles in the cell. These contacts impact on mitochondrial behavior and function as well as on a wide variety of cellular functions. Many recent advances have been made in the rapidly growing field of mitochondria contact site biology, and these advances have expanded the known functions of mitochondria contact sites in exciting and unexpected ways.

Keywords: interorganelle contacts; membrane contact sites; mitochondria contact sites.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Humans
  • Mitochondria / metabolism*
  • Organelles / metabolism