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RETRACTED: ANRIL acts as onco-lncRNA by regulation of microRNA-24/c-Myc, MEK/ERK and Wnt/β-catenin pathway in retinoblastoma

Int J Biol Macromol. 2019 May 1:128:583-592. doi: 10.1016/j.ijbiomac.2019.01.157. Epub 2019 Jan 28.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Authors. Current research findings in the authors' laboratory are in conflict with previous experimental results published in this paper. It was found that the data reported in figures 4 and 5 were not able to be replicated and so therefore the authors have decided that it is best for the scientific record to retract this paper. All the authors agree with the retraction. The authors apologise for any confusion this paper might have caused readers.

Keywords: Antisense non-coding RNA in the INK4 locus; MEK/ERK pathway; MicroRNA-24; Retinoblastoma; Wnt/β-catenin pathway; c-Myc.

Publication types

  • Retracted Publication

MeSH terms

  • Cell Movement / genetics
  • Cell Proliferation / genetics
  • Cell Survival / genetics
  • Child, Preschool
  • Female
  • Gene Expression Regulation, Neoplastic / genetics
  • Humans
  • Infant
  • MAP Kinase Signaling System / genetics*
  • Male
  • MicroRNAs / genetics*
  • Neoplasm Invasiveness
  • Proto-Oncogene Proteins c-myc / genetics*
  • RNA, Long Noncoding / genetics*
  • Retinoblastoma / genetics*
  • Retinoblastoma / pathology*
  • Wnt Signaling Pathway / genetics*

Substances

  • CDKN2B antisense RNA, human
  • MIRN24 microRNA, human
  • MYC protein, human
  • MicroRNAs
  • Proto-Oncogene Proteins c-myc
  • RNA, Long Noncoding