Predictive Processing: A Canonical Cortical Computation

Neuron. 2018 Oct 24;100(2):424-435. doi: 10.1016/j.neuron.2018.10.003.

Authors

Affiliations

¹ Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland; Faculty of Natural Sciences, University of Basel, Basel, Switzerland. Electronic address: georg.keller@fmi.ch.
² Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.

Abstract

This perspective describes predictive processing as a computational framework for understanding cortical function in the context of emerging evidence, with a focus on sensory processing. We discuss how the predictive processing framework may be implemented at the level of cortical circuits and how its implementation could be falsified experimentally. Lastly, we summarize the general implications of predictive processing on cortical function in healthy and diseased states.

Keywords: canonical microcircuit; cortex; predictive coding; predictive processing; sensory processing.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Computer Simulation*
Humans
Models, Neurological*
Neocortex / physiology*
Sensation / physiology*

Grants and funding

Wellcome Trust/United Kingdom