Zhao T - Search Results

1

N-terminal Huntingtin Knock-In Mice: Implications of Removing the N-terminal Region of Huntingtin for Therapy.

Liu X, Wang CE, Hong Y, Zhao T, Wang G, Gaertig MA, Sun M, Li S, Li XJ. Liu X, et al. Among authors: zhao t. PLoS Genet. 2016 May 20;12(5):e1006083. doi: 10.1371/journal.pgen.1006083. eCollection 2016 May. PLoS Genet. 2016. PMID: 27203582 Free PMC article.

2

Huntingtin-associated protein 1 regulates postnatal neurogenesis and neurotrophin receptor sorting.

Xiang J, Yang H, Zhao T, Sun M, Xu X, Zhou XF, Li SH, Li XJ. Xiang J, et al. Among authors: zhao t. J Clin Invest. 2014 Jan;124(1):85-98. doi: 10.1172/JCI69206. Epub 2013 Dec 20. J Clin Invest. 2014. PMID: 24355921 Free PMC article.

3

Aged monkey brains reveal the role of ubiquitin-conjugating enzyme UBE2N in the synaptosomal accumulation of mutant huntingtin.

Yin P, Tu Z, Yin A, Zhao T, Yan S, Guo X, Chang R, Zhang L, Hong Y, Huang X, Zhou J, Wang Y, Li S, Li XJ. Yin P, et al. Among authors: zhao t. Hum Mol Genet. 2015 Mar 1;24(5):1350-62. doi: 10.1093/hmg/ddu544. Epub 2014 Oct 24. Hum Mol Genet. 2015. PMID: 25343992 Free PMC article.

4

Subcellular Clearance and Accumulation of Huntington Disease Protein: A Mini-Review.

Zhao T, Hong Y, Li XJ, Li SH. Zhao T, et al. Front Mol Neurosci. 2016 Apr 21;9:27. doi: 10.3389/fnmol.2016.00027. eCollection 2016. Front Mol Neurosci. 2016. PMID: 27147961 Free PMC article. Review.

5

Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal Processes.

Zhao T, Hong Y, Li S, Li XJ. Zhao T, et al. J Neurosci. 2016 Aug 10;36(32):8317-28. doi: 10.1523/JNEUROSCI.0806-16.2016. J Neurosci. 2016. PMID: 27511006 Free PMC article.

6

Mutant Huntingtin Impairs BDNF Release from Astrocytes by Disrupting Conversion of Rab3a-GTP into Rab3a-GDP.

Hong Y, Zhao T, Li XJ, Li S. Hong Y, et al. Among authors: zhao t. J Neurosci. 2016 Aug 24;36(34):8790-801. doi: 10.1523/JNEUROSCI.0168-16.2016. J Neurosci. 2016. PMID: 27559163 Free PMC article.

7

CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington's disease.

Yang S, Chang R, Yang H, Zhao T, Hong Y, Kong HE, Sun X, Qin Z, Jin P, Li S, Li XJ. Yang S, et al. Among authors: zhao t. J Clin Invest. 2017 Jun 30;127(7):2719-2724. doi: 10.1172/JCI92087. Epub 2017 Jun 19. J Clin Invest. 2017. PMID: 28628038 Free PMC article.

8

Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins.

Zhao T, Hong Y, Yin P, Li S, Li XJ. Zhao T, et al. Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):E7803-E7811. doi: 10.1073/pnas.1710549114. Epub 2017 Aug 28. Proc Natl Acad Sci U S A. 2017. PMID: 28847953 Free PMC article.

9

Mutant Huntingtin Inhibits αB-Crystallin Expression and Impairs Exosome Secretion from Astrocytes.

Hong Y, Zhao T, Li XJ, Li S. Hong Y, et al. Among authors: zhao t. J Neurosci. 2017 Sep 27;37(39):9550-9563. doi: 10.1523/JNEUROSCI.1418-17.2017. Epub 2017 Sep 11. J Neurosci. 2017. PMID: 28893927 Free PMC article.

10

Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains.

Yin P, Guo X, Yang W, Yan S, Yang S, Zhao T, Sun Q, Liu Y, Li S, Li XJ. Yin P, et al. Among authors: zhao t. Acta Neuropathol. 2019 Jun;137(6):919-937. doi: 10.1007/s00401-019-01979-0. Epub 2019 Feb 27. Acta Neuropathol. 2019. PMID: 30810811 Free PMC article.

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