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Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression.
Gorshkova I, Zhou T, Mathew B, Jacobson JR, Takekoshi D, Bhattacharya P, Smith B, Aydogan B, Weichselbaum RR, Natarajan V, Garcia JG, Berdyshev EV. Gorshkova I, et al. Among authors: zhou t. J Lipid Res. 2012 Aug;53(8):1553-68. doi: 10.1194/jlr.M026039. Epub 2012 May 21. J Lipid Res. 2012. PMID: 22615416 Free PMC article.
Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs.
Mathew B, Jacobson JR, Berdyshev E, Huang Y, Sun X, Zhao Y, Gerhold LM, Siegler J, Evenoski C, Wang T, Zhou T, Zaidi R, Moreno-Vinasco L, Bittman R, Chen CT, LaRiviere PJ, Sammani S, Lussier YA, Dudek SM, Natarajan V, Weichselbaum RR, Garcia JG. Mathew B, et al. Among authors: zhou t. FASEB J. 2011 Oct;25(10):3388-400. doi: 10.1096/fj.11-183970. Epub 2011 Jun 28. FASEB J. 2011. PMID: 21712494 Free PMC article.
Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis.
Huang LS, Berdyshev E, Mathew B, Fu P, Gorshkova IA, He D, Ma W, Noth I, Ma SF, Pendyala S, Reddy SP, Zhou T, Zhang W, Garzon SA, Garcia JG, Natarajan V. Huang LS, et al. Among authors: zhou t. FASEB J. 2013 Apr;27(4):1749-60. doi: 10.1096/fj.12-219634. Epub 2013 Jan 11. FASEB J. 2013. PMID: 23315259 Free PMC article.
Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy.
Huang LS, Berdyshev EV, Tran JT, Xie L, Chen J, Ebenezer DL, Mathew B, Gorshkova I, Zhang W, Reddy SP, Harijith A, Wang G, Feghali-Bostwick C, Noth I, Ma SF, Zhou T, Ma W, Garcia JG, Natarajan V. Huang LS, et al. Among authors: zhou t. Thorax. 2015 Dec;70(12):1138-48. doi: 10.1136/thoraxjnl-2014-206684. Epub 2015 Aug 18. Thorax. 2015. PMID: 26286721 Free article.
Sphingosine-1-phosphate receptor-3 is a novel biomarker in acute lung injury.
Sun X, Singleton PA, Letsiou E, Zhao J, Belvitch P, Sammani S, Chiang ET, Moreno-Vinasco L, Wade MS, Zhou T, Liu B, Parastatidis I, Thomson L, Ischiropoulos H, Natarajan V, Jacobson JR, Machado RF, Dudek SM, Garcia JG. Sun X, et al. Among authors: zhou t. Am J Respir Cell Mol Biol. 2012 Nov;47(5):628-36. doi: 10.1165/rcmb.2012-0048OC. Epub 2012 Jul 5. Am J Respir Cell Mol Biol. 2012. PMID: 22771388 Free PMC article.
Role of migratory inhibition factor in age-related susceptibility to radiation lung injury via NF-E2-related factor-2 and antioxidant regulation.
Mathew B, Jacobson JR, Siegler JH, Moitra J, Blasco M, Xie L, Unzueta C, Zhou T, Evenoski C, Al-Sakka M, Sharma R, Huey B, Bulent A, Smith B, Jayaraman S, Reddy NM, Reddy SP, Fingerle-Rowson G, Bucala R, Dudek SM, Natarajan V, Weichselbaum RR, Garcia JG. Mathew B, et al. Among authors: zhou t. Am J Respir Cell Mol Biol. 2013 Aug;49(2):269-78. doi: 10.1165/rcmb.2012-0291OC. Am J Respir Cell Mol Biol. 2013. PMID: 23526214 Free PMC article.
Type 2 deiodinase and host responses of sepsis and acute lung injury.
Ma SF, Xie L, Pino-Yanes M, Sammani S, Wade MS, Letsiou E, Siegler J, Wang T, Infusino G, Kittles RA, Flores C, Zhou T, Prabhakar BS, Moreno-Vinasco L, Villar J, Jacobson JR, Dudek SM, Garcia JG. Ma SF, et al. Among authors: zhou t. Am J Respir Cell Mol Biol. 2011 Dec;45(6):1203-11. doi: 10.1165/rcmb.2011-0179OC. Epub 2011 Jun 17. Am J Respir Cell Mol Biol. 2011. PMID: 21685153 Free PMC article.
Functional promoter variants in sphingosine 1-phosphate receptor 3 associate with susceptibility to sepsis-associated acute respiratory distress syndrome.
Sun X, Ma SF, Wade MS, Acosta-Herrera M, Villar J, Pino-Yanes M, Zhou T, Liu B, Belvitch P, Moitra J, Han YJ, Machado R, Noth I, Natarajan V, Dudek SM, Jacobson JR, Flores C, Garcia JG. Sun X, et al. Among authors: zhou t. Am J Physiol Lung Cell Mol Physiol. 2013 Oct 1;305(7):L467-77. doi: 10.1152/ajplung.00010.2013. Epub 2013 Aug 2. Am J Physiol Lung Cell Mol Physiol. 2013. PMID: 23911438 Free PMC article.
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