Ohtani N - Search Results

1

Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence.

Takahashi A, Ohtani N, Yamakoshi K, Iida S, Tahara H, Nakayama K, Nakayama KI, Ide T, Saya H, Hara E. Takahashi A, et al. Among authors: ohtani n. Nat Cell Biol. 2006 Nov;8(11):1291-7. doi: 10.1038/ncb1491. Epub 2006 Oct 8. Nat Cell Biol. 2006. PMID: 17028578

2

Regulation of CDK4 activity by a novel CDK4-binding protein, p34(SEI-1).

Sugimoto M, Nakamura T, Ohtani N, Hampson L, Hampson IN, Shimamoto A, Furuichi Y, Okumura K, Niwa S, Taya Y, Hara E. Sugimoto M, et al. Among authors: ohtani n. Genes Dev. 1999 Nov 15;13(22):3027-33. doi: 10.1101/gad.13.22.3027. Genes Dev. 1999. PMID: 10580009 Free PMC article.

3

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence.

Ohtani N, Zebedee Z, Huot TJ, Stinson JA, Sugimoto M, Ohashi Y, Sharrocks AD, Peters G, Hara E. Ohtani N, et al. Nature. 2001 Feb 22;409(6823):1067-70. doi: 10.1038/35059131. Nature. 2001. PMID: 11234019

4

Epstein-Barr virus LMP1 blocks p16INK4a-RB pathway by promoting nuclear export of E2F4/5.

Ohtani N, Brennan P, Gaubatz S, Sanij E, Hertzog P, Wolvetang E, Ghysdael J, Rowe M, Hara E. Ohtani N, et al. J Cell Biol. 2003 Jul 21;162(2):173-83. doi: 10.1083/jcb.200302085. Epub 2003 Jul 14. J Cell Biol. 2003. PMID: 12860972 Free PMC article.

5

The p16INK4a-RB pathway: molecular link between cellular senescence and tumor suppression.

Ohtani N, Yamakoshi K, Takahashi A, Hara E. Ohtani N, et al. J Med Invest. 2004 Aug;51(3-4):146-53. doi: 10.2152/jmi.51.146. J Med Invest. 2004. PMID: 15460900 Free article. Review.

6

Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p53.

Maehara K, Yamakoshi K, Ohtani N, Kubo Y, Takahashi A, Arase S, Jones N, Hara E. Maehara K, et al. Among authors: ohtani n. J Cell Biol. 2005 Feb 14;168(4):553-60. doi: 10.1083/jcb.200411093. J Cell Biol. 2005. PMID: 15716376 Free PMC article.

7

Epigenetic abnormalities in cutaneous squamous cell carcinomas: frequent inactivation of the RB1/p16 and p53 pathways.

Murao K, Kubo Y, Ohtani N, Hara E, Arase S. Murao K, et al. Among authors: ohtani n. Br J Dermatol. 2006 Nov;155(5):999-1005. doi: 10.1111/j.1365-2133.2006.07487.x. Br J Dermatol. 2006. PMID: 17034532

8

Irreversibility of cellular senescence: dual roles of p16INK4a/Rb-pathway in cell cycle control.

Takahashi A, Ohtani N, Hara E. Takahashi A, et al. Among authors: ohtani n. Cell Div. 2007 Mar 7;2:10. doi: 10.1186/1747-1028-2-10. Cell Div. 2007. PMID: 17343761 Free PMC article.

9

Visualizing the dynamics of p21(Waf1/Cip1) cyclin-dependent kinase inhibitor expression in living animals.

Ohtani N, Imamura Y, Yamakoshi K, Hirota F, Nakayama R, Kubo Y, Ishimaru N, Takahashi A, Hirao A, Shimizu T, Mann DJ, Saya H, Hayashi Y, Arase S, Matsumoto M, Kazuki N, Hara E. Ohtani N, et al. Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):15034-9. doi: 10.1073/pnas.0706949104. Epub 2007 Sep 11. Proc Natl Acad Sci U S A. 2007. PMID: 17848507 Free PMC article.

10

Cellular senescence: its role in tumor suppression and aging.

Ohtani N, Mann DJ, Hara E. Ohtani N, et al. Cancer Sci. 2009 May;100(5):792-7. doi: 10.1111/j.1349-7006.2009.01123.x. Epub 2009 Mar 15. Cancer Sci. 2009. PMID: 19302284 Free PMC article. Review.

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