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PHC1 maintains pluripotency by organizing genome-wide chromatin interactions of the Nanog locus.
Chen L, Tong Q, Chen X, Jiang P, Yu H, Zhao Q, Sun L, Liu C, Gu B, Zheng Y, Fei L, Jiang X, Li W, Volpe G, Abdul MM, Guo G, Zhang J, Qian P, Sun Q, Neculai D, Esteban MA, Li C, Wen F, Ji J. Chen L, et al. Among authors: neculai d. Nat Commun. 2021 May 14;12(1):2829. doi: 10.1038/s41467-021-22871-0. Nat Commun. 2021. PMID: 33990559 Free PMC article.
An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme.
Ceccarelli DF, Tang X, Pelletier B, Orlicky S, Xie W, Plantevin V, Neculai D, Chou YC, Ogunjimi A, Al-Hakim A, Varelas X, Koszela J, Wasney GA, Vedadi M, Dhe-Paganon S, Cox S, Xu S, Lopez-Girona A, Mercurio F, Wrana J, Durocher D, Meloche S, Webb DR, Tyers M, Sicheri F. Ceccarelli DF, et al. Among authors: neculai d. Cell. 2011 Jun 24;145(7):1075-87. doi: 10.1016/j.cell.2011.05.039. Epub 2011 Jun 16. Cell. 2011. PMID: 21683433 Free article.
Lactylation stabilizes TFEB to elevate autophagy and lysosomal activity.
Huang Y, Luo G, Peng K, Song Y, Wang Y, Zhang H, Li J, Qiu X, Pu M, Liu X, Peng C, Neculai D, Sun Q, Zhou T, Huang P, Liu W. Huang Y, et al. Among authors: neculai d. J Cell Biol. 2024 Nov 4;223(11):e202308099. doi: 10.1083/jcb.202308099. Epub 2024 Aug 28. J Cell Biol. 2024. PMID: 39196068 Free PMC article.
59 results