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The lipoprotein-associated phospholipase A2 inhibitor Darapladib sensitises cancer cells to ferroptosis by remodelling lipid metabolism.
Oh M, Jang SY, Lee JY, Kim JW, Jung Y, Kim J, Seo J, Han TS, Jang E, Son HY, Kim D, Kim MW, Park JS, Song KH, Oh KJ, Kim WK, Bae KH, Huh YM, Kim SH, Kim D, Han BS, Lee SC, Hwang GS, Lee EW. Oh M, et al. Among authors: kim wk, kim d, kim sh, kim mw, kim j, kim jw. Nat Commun. 2023 Sep 15;14(1):5728. doi: 10.1038/s41467-023-41462-9. Nat Commun. 2023. PMID: 37714840 Free PMC article.
Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer.
Lee JY, Nam M, Son HY, Hyun K, Jang SY, Kim JW, Kim MW, Jung Y, Jang E, Yoon SJ, Kim J, Kim J, Seo J, Min JK, Oh KJ, Han BS, Kim WK, Bae KH, Song J, Kim J, Huh YM, Hwang GS, Lee EW, Lee SC. Lee JY, et al. Among authors: kim wk, kim mw, kim j, kim jw. Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32433-32442. doi: 10.1073/pnas.2006828117. Epub 2020 Dec 7. Proc Natl Acad Sci U S A. 2020. PMID: 33288688 Free PMC article.
Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes.
Park TJ, Park JH, Lee GS, Lee JY, Shin JH, Kim MW, Kim YS, Kim JY, Oh KJ, Han BS, Kim WK, Ahn Y, Moon JH, Song J, Bae KH, Kim DH, Lee EW, Lee SC. Park TJ, et al. Among authors: kim jy, kim wk, kim dh, kim mw, kim ys. Cell Death Dis. 2019 Nov 4;10(11):835. doi: 10.1038/s41419-019-2061-8. Cell Death Dis. 2019. PMID: 31685805 Free PMC article.
534 results