Flach J - Search Results

1

DNA Damage and DNA Damage Response in Chronic Myeloid Leukemia.

Popp HD, Kohl V, Naumann N, Flach J, Brendel S, Kleiner H, Weiss C, Seifarth W, Saussele S, Hofmann WK, Fabarius A. Popp HD, et al. Among authors: flach j. Int J Mol Sci. 2020 Feb 11;21(4):1177. doi: 10.3390/ijms21041177. Int J Mol Sci. 2020. PMID: 32053969 Free PMC article.

2

Accumulation of DNA damage and alteration of the DNA damage response in monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia.

Popp HD, Flach J, Brendel S, Ruppenthal S, Kleiner H, Seifarth W, Schneider S, Schulze TJ, Weiss C, Wenz F, Hofmann WK, Fabarius A. Popp HD, et al. Among authors: flach j. Leuk Lymphoma. 2019 Mar;60(3):795-804. doi: 10.1080/10428194.2018.1498494. Epub 2018 Oct 31. Leuk Lymphoma. 2019. PMID: 30376743

3

Comparative analysis of clonal hematopoiesis of multipotent stem cells in healthy elderly in blood and bone marrow.

Jann JC, Nolte F, Mossner M, Flach J, Altrock E, Schmitt N, Röhl H, Jawhar A, Neumann U, Nowak V, Danner J, Obländer J, Palme I, Hofmann WK, Nowak D. Jann JC, et al. Among authors: flach j. Leuk Res. 2019 Jul;82:15-18. doi: 10.1016/j.leukres.2019.05.005. Epub 2019 May 16. Leuk Res. 2019. PMID: 31132434 No abstract available.

4

Antileukemic Efficacy in Vitro of Talazoparib and APE1 Inhibitor III Combined with Decitabine in Myeloid Malignancies.

Kohl V, Flach J, Naumann N, Brendel S, Kleiner H, Weiss C, Seifarth W, Nowak D, Hofmann WK, Fabarius A, Popp HD. Kohl V, et al. Among authors: flach j. Cancers (Basel). 2019 Oct 3;11(10):1493. doi: 10.3390/cancers11101493. Cancers (Basel). 2019. PMID: 31623402 Free PMC article.

5

Separase activity distribution can be a marker of major molecular response and proliferation of CD34⁺ cells in TKI-treated chronic myeloid leukemia patients.

Spiess B, Kleiner H, Flach J, Fabarius A, Saussele S, Hofmann WK, Seifarth W. Spiess B, et al. Among authors: flach j. Ann Hematol. 2020 May;99(5):991-1006. doi: 10.1007/s00277-020-04007-4. Epub 2020 Apr 6. Ann Hematol. 2020. PMID: 32253454 Free PMC article. Clinical Trial.

6

RNA-sequencing of acute promyelocytic leukemia primary blasts reveals novel molecular biomarkers of early death events.

Jann JC, Streuer A, Hecht A, Nolte F, Nowak V, Danner J, Obländer J, Palme I, Lengfelder E, Platzbecker U, Hofmann WK, Flach J, Nowak D. Jann JC, et al. Among authors: flach j. Leuk Lymphoma. 2020 Dec;61(13):3066-3077. doi: 10.1080/10428194.2020.1797006. Epub 2020 Jul 29. Leuk Lymphoma. 2020. PMID: 32723198

7

Replication stress signaling is a therapeutic target in myelodysplastic syndromes with splicing factor mutations.

Flach J, Jann JC, Knaflic A, Riabov V, Streuer A, Altrock E, Xu Q, Schmitt N, Obländer J, Nowak V, Danner J, Mehralivand A, Hofmann F, Palme I, Jawhar A, Wuchter P, Metzgeroth G, Nolte F, Hofmann WK, Nowak D. Flach J, et al. Haematologica. 2021 Nov 1;106(11):2906-2917. doi: 10.3324/haematol.2020.254193. Haematologica. 2021. PMID: 33054116 Free PMC article.

8

Genotoxic Bystander Signals from Irradiated Human Mesenchymal Stromal Cells Mainly Localize in the 10-100 kDa Fraction of Conditioned Medium.

Kohl V, Fabarius A, Drews O, Bierbaum M, Jawhar A, Darwich A, Weiss C, Flach J, Brendel S, Kleiner H, Seifarth W, Hofmann WK, Popp HD. Kohl V, et al. Among authors: flach j. Cells. 2021 Apr 7;10(4):827. doi: 10.3390/cells10040827. Cells. 2021. PMID: 33916980 Free PMC article.

9

Proteins Marking the Sequence of Genotoxic Signaling from Irradiated Mesenchymal Stromal Cells to CD34+ Cells.

Kohl V, Drews O, Costina V, Bierbaum M, Jawhar A, Roehl H, Weiss C, Brendel S, Kleiner H, Flach J, Spiess B, Seifarth W, Nowak D, Hofmann WK, Fabarius A, Popp HD. Kohl V, et al. Among authors: flach j. Int J Mol Sci. 2021 May 29;22(11):5844. doi: 10.3390/ijms22115844. Int J Mol Sci. 2021. PMID: 34072546 Free PMC article.

10

Preclinical evaluation of eltrombopag in a PDX model of myelodysplastic syndromes.

Schmitt N, Jann JC, Altrock E, Flach J, Danner J, Uhlig S, Streuer A, Knaflic A, Riabov V, Xu Q, Mehralivand A, Palme I, Nowak V, Obländer J, Weimer N, Haselmann V, Jawhar A, Darwich A, Weis CA, Marx A, Steiner L, Jawhar M, Metzgeroth G, Boch T, Nolte F, Hofmann WK, Nowak D. Schmitt N, et al. Among authors: flach j. Leukemia. 2022 Jan;36(1):236-247. doi: 10.1038/s41375-021-01327-w. Epub 2021 Jun 25. Leukemia. 2022. PMID: 34172896 Free PMC article.

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