Copple BL - Search Results

1

Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules.

Copple BL, Li T. Copple BL, et al. Pharmacol Res. 2016 Feb;104:9-21. doi: 10.1016/j.phrs.2015.12.007. Epub 2015 Dec 17. Pharmacol Res. 2016. PMID: 26706784 Free PMC article. Review.

2

Upregulation of early growth response factor-1 by bile acids requires mitogen-activated protein kinase signaling.

Allen K, Kim ND, Moon JO, Copple BL. Allen K, et al. Among authors: copple bl. Toxicol Appl Pharmacol. 2010 Feb 15;243(1):63-7. doi: 10.1016/j.taap.2009.11.013. Epub 2009 Nov 17. Toxicol Appl Pharmacol. 2010. PMID: 19931294 Free PMC article.

3

Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis.

Allen K, Jaeschke H, Copple BL. Allen K, et al. Among authors: copple bl. Am J Pathol. 2011 Jan;178(1):175-86. doi: 10.1016/j.ajpath.2010.11.026. Epub 2010 Dec 23. Am J Pathol. 2011. PMID: 21224055 Free PMC article.

4

Effect of bile duct ligation on bile acid composition in mouse serum and liver.

Zhang Y, Hong JY, Rockwell CE, Copple BL, Jaeschke H, Klaassen CD. Zhang Y, et al. Among authors: copple bl. Liver Int. 2012 Jan;32(1):58-69. doi: 10.1111/j.1478-3231.2011.02662.x. Epub 2011 Oct 17. Liver Int. 2012. PMID: 22098667 Free PMC article.

5

IL-17A synergistically enhances bile acid-induced inflammation during obstructive cholestasis.

O'Brien KM, Allen KM, Rockwell CE, Towery K, Luyendyk JP, Copple BL. O'Brien KM, et al. Among authors: copple bl. Am J Pathol. 2013 Nov;183(5):1498-1507. doi: 10.1016/j.ajpath.2013.07.019. Epub 2013 Sep 5. Am J Pathol. 2013. PMID: 24012680 Free PMC article.

6

Early growth response factor-1 is critical for cholestatic liver injury.

Kim ND, Moon JO, Slitt AL, Copple BL. Kim ND, et al. Among authors: copple bl. Toxicol Sci. 2006 Apr;90(2):586-95. doi: 10.1093/toxsci/kfj111. Epub 2006 Jan 19. Toxicol Sci. 2006. PMID: 16423862

7

Hypoxia-inducible factor activation in myeloid cells contributes to the development of liver fibrosis in cholestatic mice.

Copple BL, Kaska S, Wentling C. Copple BL, et al. J Pharmacol Exp Ther. 2012 May;341(2):307-16. doi: 10.1124/jpet.111.189340. Epub 2012 Jan 23. J Pharmacol Exp Ther. 2012. PMID: 22271822 Free PMC article.

8

Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice.

Yang M, Ramachandran A, Yan HM, Woolbright BL, Copple BL, Fickert P, Trauner M, Jaeschke H. Yang M, et al. Among authors: copple bl. Toxicol Lett. 2014 Jan 13;224(2):186-95. doi: 10.1016/j.toxlet.2013.10.030. Epub 2013 Nov 2. Toxicol Lett. 2014. PMID: 24188933 Free PMC article.

9

Coagulation-driven platelet activation reduces cholestatic liver injury and fibrosis in mice.

Joshi N, Kopec AK, O'Brien KM, Towery KL, Cline-Fedewa H, Williams KJ, Copple BL, Flick MJ, Luyendyk JP. Joshi N, et al. Among authors: copple bl. J Thromb Haemost. 2015 Jan;13(1):57-71. doi: 10.1111/jth.12770. Epub 2014 Dec 11. J Thromb Haemost. 2015. PMID: 25353084 Free PMC article.

10

Hypoxia upregulates Cxcl12 in hepatocytes by a complex mechanism involving hypoxia-inducible factors and transforming growth factor-β.

Strickland J, Garrison D, Copple BL. Strickland J, et al. Among authors: copple bl. Cytokine. 2020 Mar;127:154986. doi: 10.1016/j.cyto.2020.154986. Epub 2020 Jan 14. Cytokine. 2020. PMID: 31951966 Free PMC article.

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