Up All Night

Pilot (Season 1, Episode 1)

TV-14

TV Episode | 22 min | Comedy

Reagan Brinkley is a loving wife, successful career woman, life of the party and, most recently, mom. Determined not to compromise her career or cool reputation to the clichés of motherhood, Reagan adjusts to life with a baby and returns ...See moreReagan Brinkley is a loving wife, successful career woman, life of the party and, most recently, mom. Determined not to compromise her career or cool reputation to the clichés of motherhood, Reagan adjusts to life with a baby and returns to work with the support of her stay-at-home husband, Chris. As Reagan and Chris figure out their new life, self-doubt, sleep deprivation and the pressure of today's parenting protocols rattle their confidence. What's more, the endless needs of Reagan's boss, ambitious but vulnerable talk-show host Ava, threaten to throw Reagan off balance. Written by NBC Publicity See less

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Cast	+ Add Cast
9 cast members

Name	Known for
Christina Applegate Reagan Brinkley Reagan Brinkley See fewer	Don't Tell Mom the Babysitter's Dead (1991)
Maya Rudolph Ava Alexander Ava Alexander See fewer	Bridesmaids (I) (2011)
Will Arnett Chris Brinkley Chris Brinkley See fewer	The Lego Batman Movie (2017)
Nick Cannon Calvin Calvin See fewer	Drumline (2002)
Jennifer Hall Missy Missy See fewer	Up All Night (2011)
Matt Lauer Self Self See fewer	Land of the Lost (2009)
Connie Sawyer Shopper Shopper See fewer	Dumb and Dumber (1994)
Beau Dunn Katie Katie See fewer	Beau's Babes Campaign (2017)
Dustin McKamie Hipster (uncredited) Hipster (uncredited) See fewer	Thor: Love and Thunder (2022)