1. Keiya YOSHIMURA - Anime News Network
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2. General Discussions - Keiya Yoshimura — The Movie Database ...
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The Movie Database (TMDB) is a popular, user editable database for movies and TV shows.
3. Keiya Yoshimura | AniBase.Net
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The website does not have full-time moderators. If you find errors, infringements, or pornographic content, you can manually edit it out or click "Contact Us" to provide feedback and wait for us to address it.
4. Keiya Kawai | School Girls Simulator Wiki - Fandom
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Keiya Kawai (河合けいや) is a student attending the Senior High School in Class 3-4. Keiya has green eyes and green hair with long bangs. His uniform is customizable, and, like all other students, he carries a randomized bag. When visiting the Beach (Sea), he automatically equips the School Pool Uniform. If he visits the Hot Spring Bathhouse, he will change into a light tan towel. His height is 172cm (5'8"). Keiya doesn't have a house. Upon starting the game from the Main Menu, Keiya spawns at the Ba
5. Keiya Kawai - School Girls Simulator Wiki - Fandom
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School Girls Simulator is a School Simulation game made by Meromsoft!
6. Discuss Keiya Yoshimura — The Movie Database (TMDB)
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The Movie Database (TMDB) is a popular, user editable database for movies and TV shows.
7. Virological characteristics of the SARS-CoV-2 Omicron XBB.1.5 variant
... Keiya Uriu); JSPS Leading Initiative for Excellent Young Researchers (LEADER) ... Yoshimura, Kyoko Yasuda, Keiko Iida, Naomi Ohsumi, Adam P. Strange ...
Circulation of SARS-CoV-2 Omicron XBB has resulted in the emergence of XBB.1.5, a new Variant of Interest. Our phylogenetic analysis suggests that XBB.1.5 evolved from XBB.1 by acquiring the S486P spike (S) mutation, subsequent to the acquisition of ...
8. Structural basis for receptor-binding domain mobility of the spike in ...
Movies were collected on a Krios G4 (Thermo Fisher Scientific) operated ... , Kaoru Usui, Wilaiporn Saikruang, Spyridon Lytras, Keiya Uriu, Ryo Yoshimura ...
Since 2019, SARS-CoV-2 has undergone mutations, resulting in pandemic and epidemic waves. The SARS-CoV-2 spike protein, crucial for cellular entry, binds to the ACE2 receptor exclusively when its receptor-binding domain (RBD) adopts the ...
9. Structural basis for receptor-binding domain mobility of the spike in ...
Oct 7, 2024 · Hinay Jr., Kaoru Usui, Wilaiporn Saikruang, Spyridon Lytras, Keiya Uriu, Ryo Yoshimura ... Supplementary Movie 1 · Supplementary Movie 2 ...
Since 2019, SARS-CoV-2 has undergone mutations, resulting in pandemic and epidemic waves. The SARS-CoV-2 spike protein, crucial for cellular entry, binds to the ACE2 receptor exclusively when its receptor-binding domain (RBD) adopts the up-conformation. However, whether ACE2 also interacts with the RBD in the down-conformation to facilitate the conformational shift to RBD-up remains unclear. Herein, we present the structures of the BA.2.86 and the JN.1 spike proteins bound to ACE2. Notably, we successfully observed the ACE2-bound down-RBD, indicating an intermediate structure before the RBD-up conformation. The wider and mobile angle of RBDs in the up-state provides space for ACE2 to interact with the down-RBD, facilitating the transition to the RBD-up state. The K356T, but not N354-linked glycan, contributes to both of infectivity and neutralizing-antibody evasion in BA.2.86. These structural insights the spike-protein dynamics would help understand the mechanisms underlying SARS-CoV-2 infection and its neutralization. JN.1 lineage is a globally dominant variant of SARS-CoV-2. Here, the authors examine structural insights into the BA.2.86 and JN.1 spike dynamics to help understand the mechanisms underlying SARS-CoV-2 infection and its neutralizing-antibody evasion.
10. Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant
Oct 21, 2023 · ... Yoshimura, Hesham Nasser, Michael Jonathan, Olivia Putri, Yoonjin ... Keiya Uriu); JSPS Leading Initiative for Excellent Young ...
In middle-late 2023, a sublineage of SARS-CoV-2 Omicron XBB, EG.5.1 (a progeny of XBB.1.9.2), is spreading rapidly around the world. Here, we performed multiscale investigations to reveal virological features of newly emerging EG.5.1 variant. Our phylogenetic-epidemic dynamics modeling suggested that two hallmark substitutions of EG.5.1, S:F456L and ORF9b:I5T, are critical to the increased viral fitness. Experimental investigations addressing the growth kinetics, sensitivity to clinically available antivirals, fusogenicity and pathogenicity of EG.5.1 suggested that the virological features of EG.5.1 is comparable to that of XBB.1.5. However, the cryo-electron microscopy reveals the structural difference between the spike proteins of EG.5.1 and XBB.1.5. We further assessed the impact of ORF9b:I5T on viral features, but it was almost negligible at least in our experimental setup. Our multiscale investigations provide the knowledge for understanding of the evolution trait of newly emerging pathogenic viruses in the human population. ### Competing Interest Statement Yuki Yamamoto and Tetsuharu Nagamoto are founders and shareholders of HiLung, Inc. Yuki Yamamoto is a co-inventor of patents (PCT/JP2016/057254; "Method for inducing differentiation of alveolar epithelial cells", PCT/JP2016/059786, "Method of producing airway epithelial cells"). Jumpei Ito has consulting fees and honoraria for lectures from Takeda Pharmaceutical Co. Ltd. Kei Sato has consulting fees from Moderna Jap...
11. EMDB-34224: SARS-CoV-2 BA.2.75 spike glycoprotein in complex with ...
... Keiya Uriu / Yusuke Kosugi / Shigeru Fujita / Maya Shofa / Mst Monira Begum ... Yoshimura / Takamasa Ueno / Gideon Schreiber / Akifumi Takaori-Kondo ...
12. [PDF] International Symposium
Dec 31, 2011 · Yoshimura (Toyota Tech. Inst.) Local Arrangement Committee. Chair ... Keiya-doro. Shin ohashi-dori. Main entrance to lchinge to Higashi ...
13. High Energy Physics - Theory Jun 2022 - arXiv
Jun 14, 2022 · Keiya Ishiguro, Hiroshi Okada, Hajime Otsuka. Comments: 31 pages, 18 ... Benjamin Doyon, Gabriele Perfetto, Tomohiro Sasamoto, Takato Yoshimura.
Title: Open String Probe in Soft Hair BTZ
14. Virological characteristics of the SARS-CoV-2 XBB variant derived from ...
... Yoshimura R ,. Yasuda K ,. Iida K ,. Ohsumi N ,. Strange AP ,. Takahashi O ... Keiya Uriu,#3,4 Jiri Zahradnik,#5,6 Izumi Kida,#7 Yuki Anraku,#8 Hesham ...
Europe PMC is an archive of life sciences journal literature.
15. The Japanese Economic Review - IDEAS/RePEc
by Hiroshi Goto & Keiya Minamimura. September 2019, Volume 70, Issue 3 ... by Naoya Sueishi & Arihiro Yoshimura; 364-393 Effects of Anticipated Fiscal ...
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:bla:jecrev. See general information about how to correct material in RePEc.
16. Virological characteristics of the SARS-CoV-2 XBB variant derived from ...
May 16, 2023 · ... Yoshimura, Kyoko Yasuda, Keiko Iida, Naomi Ohsumi, Adam P. ... Keiya Uriu, Yusuke Kosugi, Shigeru Fujita & Kei Sato. Department of ...
In late 2022, SARS-CoV-2 Omicron subvariants have become highly diversified, and XBB is spreading rapidly around the world. Our phylogenetic analyses suggested that XBB emerged through the recombination of two cocirculating BA.2 lineages, BJ.1 and BM.1.1.1 (a progeny of BA.2.75), during the summer of 2022. XBB.1 is the variant most profoundly resistant to BA.2/5 breakthrough infection sera to date and is more fusogenic than BA.2.75. The recombination breakpoint is located in the receptor-binding domain of spike, and each region of the recombinant spike confers immune evasion and increases fusogenicity. We further provide the structural basis for the interaction between XBB.1 spike and human ACE2. Finally, the intrinsic pathogenicity of XBB.1 in male hamsters is comparable to or even lower than that of BA.2.75. Our multiscale investigation provides evidence suggesting that XBB is the first observed SARS-CoV-2 variant to increase its fitness through recombination rather than substitutions. XBB is the first recombinant, globally dominant variant of SARS-CoV-2. Here, the authors examine the variant’s origins and virological properties, showing it is the first example of SARS-CoV-2 improving its fitness through recombination.
17. japanese research activities: Topics by Science.gov
Nagai, Sumimasa; Ozawa, Keiya. 2017-01-01. In Japan, the Pharmaceuticals and ... Yoshimura, Yukio; Ouchi, Yasuyoshi; Ito, Hideki. 2012-04-01. A decline in ...
18. [PDF] Contents
Keiya Nishida is a Professor in the Department of Mechanical Systems Engineering, ... Yoshimura (SUZUKI MOTOR CORPORATION). 20199573. A Study of a 2-Stroke ...
19. Notable Graduates
□Yoshimura Tsunesuke. □Hirooka Tomoo. □Minato Moriatsu. □Sakata Katsuro ... □Kanda keiya. □Hirano Ryuichi. □Murayama Matsuo. □Oshima Joji. □Uchida ...
20. [PDF] Sustainability Report
Keiya Furukawa. Value +a Group, Investment. Department. Fund Manager. [Focus point for work]. I tend to become absorbed in things, so never forget to take a ...