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WO2007058568A3 - Sels et melanges d'acide 9-oxoacridine-10-acetique et de 1-alkylamino-1-desoxypolyols, compositions pharmaceutiques les contenant, et methodes de traitement associees - Google Patents

Sels et melanges d'acide 9-oxoacridine-10-acetique et de 1-alkylamino-1-desoxypolyols, compositions pharmaceutiques les contenant, et methodes de traitement associees Download PDF

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Publication number
WO2007058568A3
WO2007058568A3 PCT/RU2006/000614 RU2006000614W WO2007058568A3 WO 2007058568 A3 WO2007058568 A3 WO 2007058568A3 RU 2006000614 W RU2006000614 W RU 2006000614W WO 2007058568 A3 WO2007058568 A3 WO 2007058568A3
Authority
WO
WIPO (PCT)
Prior art keywords
oxoacridine
desoxy
alkylamino
polyols
acetic acid
Prior art date
Application number
PCT/RU2006/000614
Other languages
English (en)
French (fr)
Other versions
WO2007058568A2 (en
Inventor
Kirill Gennadievich Surkov
Original Assignee
Ephag As
Kirill Gennadievich Surkov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to MX2008006545A priority Critical patent/MX2008006545A/es
Priority to US12/094,479 priority patent/US7846939B2/en
Priority to SI200630895T priority patent/SI1970372T1/sl
Priority to DK06843969.4T priority patent/DK1970372T3/da
Priority to DE602006018065T priority patent/DE602006018065D1/de
Priority to CN2007800027017A priority patent/CN101370783B/zh
Priority to AT06843969T priority patent/ATE486852T1/de
Priority to PL06843969T priority patent/PL1970372T3/pl
Application filed by Ephag As, Kirill Gennadievich Surkov filed Critical Ephag As
Priority to CA002631166A priority patent/CA2631166A1/en
Priority to EP06843969A priority patent/EP1970372B1/en
Priority to BRPI0620530-5A priority patent/BRPI0620530A2/pt
Publication of WO2007058568A2 publication Critical patent/WO2007058568A2/ru
Publication of WO2007058568A3 publication Critical patent/WO2007058568A3/ru
Priority to NO20082727A priority patent/NO20082727L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
PCT/RU2006/000614 2005-11-21 2006-11-17 Salts of 9-oxoacridine-10-acetic acid with 1-alkylamino-1-desoxy-polyols WO2007058568A2 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
AT06843969T ATE486852T1 (de) 2005-11-21 2006-11-17 Salze von 9-oxoacridin-10-essigsäure mit 1- alkylamino-1-desoxypolyolen
SI200630895T SI1970372T1 (sl) 2005-11-21 2006-11-17 Soli 9-oksoakridin-10-ocetne kisline z 1-alkilamino-1-deoksi-polioli
DK06843969.4T DK1970372T3 (da) 2005-11-21 2006-11-17 Salte af 9-oxoacridin-10-eddikesyre med 1-alkylamino-1-deoxy-polyoler
DE602006018065T DE602006018065D1 (de) 2005-11-21 2006-11-17 Salze von 9-oxoacridin-10-essigsäure mit 1-alkylamino-1-desoxypolyolen
CN2007800027017A CN101370783B (zh) 2005-11-21 2006-11-17 9-氧代吖啶-10-乙酸和1-烷基氨基-1-脱氧多羟基化合物的盐和混合物、包含其的药物组合物以及治疗方法
MX2008006545A MX2008006545A (es) 2005-11-21 2006-11-17 Sales del acido 9-oxoacridine-10-acetico con 1-alkilamino-1-desoxi -poliols.
EP06843969A EP1970372B1 (en) 2005-11-21 2006-11-17 Salts of 9-oxoacridine-10-acetic acid with 1-alkylamno-1-desoxy-polyols
PL06843969T PL1970372T3 (pl) 2005-11-21 2006-11-17 Sole kwasu 9-oksoakrydyno-10-octowego z 1-alkiloamino-1-deoksypoliolami
CA002631166A CA2631166A1 (en) 2005-11-21 2006-11-17 Salts and mixture of -9-oxoacridine-10-acetic acid with 1-alkylamino-1-desoxy-polyols, pharmaceutical compositions containing said agents and treatment methods
US12/094,479 US7846939B2 (en) 2005-11-21 2006-11-17 Salts and mixture of 9-oxoacridine-10-acetic acid with 1-alkylamino-1-desoxy-polyols, pharmaceutical compositions containing said agents and treatment methods
BRPI0620530-5A BRPI0620530A2 (pt) 2005-11-21 2006-11-17 sais e misturas de 9-oxioacridona-10-ácido acético e 1-alquilamina-1-deoxipolióis, composições farmacêuticas e métodos para tratamento
NO20082727A NO20082727L (no) 2005-11-21 2008-06-19 Salter av 9-oksoakridin-10-eddiksyre med 1-alkylamino-1-deoksypolyoler

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2005136819/04A RU2326115C2 (ru) 2005-11-21 2005-11-21 Соли 1-алкиламино-1-дезоксиполиолов с 9-оксоакридин-10-уксусной кислотой, лекарственные препараты на их основе, применение, способы профилактики и лечения
RU2005136819 2005-11-21

Publications (2)

Publication Number Publication Date
WO2007058568A2 WO2007058568A2 (en) 2007-05-24
WO2007058568A3 true WO2007058568A3 (fr) 2007-10-04

Family

ID=38049089

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2006/000614 WO2007058568A2 (en) 2005-11-21 2006-11-17 Salts of 9-oxoacridine-10-acetic acid with 1-alkylamino-1-desoxy-polyols

Country Status (17)

Country Link
US (1) US7846939B2 (ru)
EP (1) EP1970372B1 (ru)
KR (1) KR20080071182A (ru)
CN (1) CN101370783B (ru)
AT (1) ATE486852T1 (ru)
BR (1) BRPI0620530A2 (ru)
CA (1) CA2631166A1 (ru)
DE (1) DE602006018065D1 (ru)
DK (1) DK1970372T3 (ru)
ES (1) ES2355435T3 (ru)
MX (1) MX2008006545A (ru)
NO (1) NO20082727L (ru)
PL (1) PL1970372T3 (ru)
RU (1) RU2326115C2 (ru)
SI (1) SI1970372T1 (ru)
UA (1) UA93529C2 (ru)
WO (1) WO2007058568A2 (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2265117B1 (en) * 2008-04-16 2017-06-07 Howard University Inhibitors of protein phosphatase-1 and uses thereof
PH12014500832A1 (en) 2011-10-21 2022-12-02 Abbvie Inc Methods for treating hcv
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
JP5677646B2 (ja) 2011-10-21 2015-02-25 アッヴィ・インコーポレイテッド Ｈｃｖの治療に使用するためのｄａａの（例えばａｂｔ−０７２もしくはａｂｔ−３３３との）併用治療
EP3448392A4 (en) 2016-04-28 2020-01-15 Emory University ALCYNE-CONTAINING NUCLEOTIDES AND NUCLEOSIDES THERAPEUTIC COMPOSITIONS AND USES THEREOF
RU2730530C1 (ru) * 2019-10-29 2020-08-24 Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" Новое химическое соединение L-лизина 9-оксоакридинил-10-ацетат, стимулирующее продукцию интерлейкина-24 и фактора некроза опухолей - бета
RU2753136C1 (ru) * 2020-10-15 2021-08-11 Оксана Владимировна Владимирова Способ аутодермопластики расщепленным кожным лоскутом для восстановления кожного покрова при ожогах

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2135474C1 (ru) * 1998-08-19 1999-08-27 Травкин Олег Викторович Соли 1-дезокси-1-n-метиламиногексаспиртов с n-акридонуксусной кислотой, обладающие иммуномодулирующей активностью, и лекарственное средство на их основе

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2031650C1 (ru) 1992-03-17 1995-03-27 Гринберг Григорий Ефимович Противовирусное лекарственное средство и способ его получения
RU2020941C1 (ru) 1992-07-06 1994-10-15 Олег Викторович Травкин Способ получения противовирусного средства
RU2036198C1 (ru) 1993-04-01 1995-05-27 Товарищество с ограниченной ответственностью "Полисан" N-МЕТИЛ-N-( α,D -ГЛЮКОПИРАНОЗИЛ) АММОНИЯ-2-(АКРИДОН-9-ОН-10-ИЛ)АЦЕТАТ(ЦИКЛОФЕРОН), ОБЛАДАЮЩИЙ ИНТЕРФЕРОНОГЕННОЙ, ПРОТИВОВИРУСНОЙ, В ТОМ ЧИСЛЕ АНТИВИЧ, АНТИПАРАЗИТАРНОЙ, АНТИПРОМОТОРНОЙ И РАДИОПРОТЕКТИВНОЙ АКТИВНОСТЬЮ
RU2182004C1 (ru) 2001-02-22 2002-05-10 Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" Лекарственный препарат для парентерального применения
RU2197248C2 (ru) 2001-03-20 2003-01-27 Травкин Олег Викторович Лекарственный препарат, обладающий иммуномоделирующим, иммунокоррегирующим, противопаразитарным, противосклеротическим, противовирусным, противобактериальным, противогрибковым, противовоспалительным и противоопухолевым действием, и способ его приготовления

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2135474C1 (ru) * 1998-08-19 1999-08-27 Травкин Олег Викторович Соли 1-дезокси-1-n-метиламиногексаспиртов с n-акридонуксусной кислотой, обладающие иммуномодулирующей активностью, и лекарственное средство на их основе

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200033, Derwent World Patents Index; AN 386170 *

Also Published As

Publication number Publication date
WO2007058568A2 (en) 2007-05-24
EP1970372B1 (en) 2010-11-03
CN101370783B (zh) 2013-03-27
US7846939B2 (en) 2010-12-07
SI1970372T1 (sl) 2011-04-29
CN101370783A (zh) 2009-02-18
RU2326115C2 (ru) 2008-06-10
DK1970372T3 (da) 2011-02-07
ATE486852T1 (de) 2010-11-15
UA93529C2 (ru) 2011-02-25
DE602006018065D1 (de) 2010-12-16
BRPI0620530A2 (pt) 2011-11-16
US20100144780A1 (en) 2010-06-10
CA2631166A1 (en) 2007-05-24
EP1970372A2 (en) 2008-09-17
MX2008006545A (es) 2009-01-16
RU2005136819A (ru) 2007-05-27
PL1970372T3 (pl) 2011-04-29
KR20080071182A (ko) 2008-08-01
NO20082727L (no) 2008-08-20
ES2355435T3 (es) 2011-03-25

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