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WO2001075152A3 - Detecteur permettant de detecter des biopolymeres macromoleculaires, systeme de detecteurs, procede de detection de biopolymeres macromoleculaires et procede de production d'un detecteur permettant de detecter des biopolymeres macromoleculaires - Google Patents

Detecteur permettant de detecter des biopolymeres macromoleculaires, systeme de detecteurs, procede de detection de biopolymeres macromoleculaires et procede de production d'un detecteur permettant de detecter des biopolymeres macromoleculaires Download PDF

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Publication number
WO2001075152A3
WO2001075152A3 PCT/DE2001/001245 DE0101245W WO0175152A3 WO 2001075152 A3 WO2001075152 A3 WO 2001075152A3 DE 0101245 W DE0101245 W DE 0101245W WO 0175152 A3 WO0175152 A3 WO 0175152A3
Authority
WO
WIPO (PCT)
Prior art keywords
sensor
macromolecular biopolymers
detecting macromolecular
detecting
biopolymers
Prior art date
Application number
PCT/DE2001/001245
Other languages
German (de)
English (en)
Other versions
WO2001075152A2 (fr
Inventor
Franz Hofmann
Richard Johannes Luyken
Original Assignee
Infineon Technologies Ag
Franz Hofmann
Richard Johannes Luyken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Infineon Technologies Ag, Franz Hofmann, Richard Johannes Luyken filed Critical Infineon Technologies Ag
Publication of WO2001075152A2 publication Critical patent/WO2001075152A2/fr
Publication of WO2001075152A3 publication Critical patent/WO2001075152A3/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00614—Delimitation of the attachment areas
    • B01J2219/00621—Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00623—Immobilisation or binding
    • B01J2219/00626—Covalent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00702—Processes involving means for analysing and characterising the products
    • B01J2219/00704—Processes involving means for analysing and characterising the products integrated with the reactor apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne un détecteur comprenant une première couche, qui présente un système de détection et permet de détecter des ondes électromagnétiques, ainsi qu'une seconde couche, qui présente une tranchée. Cette tranchée est placée sur le système de détection, de façon que les ondes électromagnétiques peuvent être détectées par le système de détection. Au moins une paroi latérale de ladite tranchée présente une zone de retenue, qui permet de retenir des molécules pouvant se lier à des biopolymères macromoléculaires.
PCT/DE2001/001245 2000-03-30 2001-03-29 Detecteur permettant de detecter des biopolymeres macromoleculaires, systeme de detecteurs, procede de detection de biopolymeres macromoleculaires et procede de production d'un detecteur permettant de detecter des biopolymeres macromoleculaires WO2001075152A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10015821.8 2000-03-30
DE10015821A DE10015821A1 (de) 2000-03-30 2000-03-30 Sensor zum Erfassen von makromolekularen Biopolymeren, Sensoranordnung, Verfahren zum Erfassen von makromolekularen Biopolymeren und Verfahren zum Herstellen eines Sensors zum Erfassen von makromolekularen Biopolymeren

Publications (2)

Publication Number Publication Date
WO2001075152A2 WO2001075152A2 (fr) 2001-10-11
WO2001075152A3 true WO2001075152A3 (fr) 2002-04-04

Family

ID=7636971

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2001/001245 WO2001075152A2 (fr) 2000-03-30 2001-03-29 Detecteur permettant de detecter des biopolymeres macromoleculaires, systeme de detecteurs, procede de detection de biopolymeres macromoleculaires et procede de production d'un detecteur permettant de detecter des biopolymeres macromoleculaires

Country Status (2)

Country Link
DE (1) DE10015821A1 (fr)
WO (1) WO2001075152A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10161529A1 (de) * 2001-12-14 2003-07-03 Infineon Technologies Ag Biosensor zum Erfassen von makromolekularen Biopolymeren, Sensoranordnung mit einem Biosensor, Verfahren zur Herstellung des Biosensors und Verfahren zum Erfassen von Nukleinsäuremolekülen mittels mindestens einer Einheit zum Immobilisieren von Nukleinsäuren
DE10221885B4 (de) * 2002-05-16 2005-12-29 Infineon Technologies Ag Sensor-Einheit, Sensor-Anordnung und Verfahren zum Betreiben einer Sensor-Einheit
EP1406090A1 (fr) * 2002-10-02 2004-04-07 Infineon Technologies AG Capteur optoélectronique, particulièrment pour la détection de biopolymères macromoleculaires
DE102008057067A1 (de) * 2008-11-13 2010-05-20 BF-BIOlabs Schneider und Zeltz GbR (Vertretungsberechtigten Gesellschafter: Dr. Patric Zeltz 79211 Denzlingen und Stephan Schneider 79211 Denzlingen Vorrichtung für die Durchführung von Mikroarray-Experimenten

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022678A2 (fr) * 1992-04-23 1993-11-11 Massachusetts Institute Of Technology Procedes et appareil optiques et electriques de detection de molecules
FR2747786A1 (fr) * 1996-04-17 1997-10-24 Motorola Inc Dispositif integre pour la detection moleculaire optique et procede de cette detection
WO1999027140A1 (fr) * 1997-11-26 1999-06-03 Lockheed Martin Energy Research Corporation Microsysteme sous forme de biopuce a circuit integre

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4408352C2 (de) * 1994-03-12 1996-02-08 Meinhard Prof Dr Knoll Miniaturisierter stofferkennender Durchflußsensor sowie Verfahren zu seiner Herstellung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022678A2 (fr) * 1992-04-23 1993-11-11 Massachusetts Institute Of Technology Procedes et appareil optiques et electriques de detection de molecules
FR2747786A1 (fr) * 1996-04-17 1997-10-24 Motorola Inc Dispositif integre pour la detection moleculaire optique et procede de cette detection
WO1999027140A1 (fr) * 1997-11-26 1999-06-03 Lockheed Martin Energy Research Corporation Microsysteme sous forme de biopuce a circuit integre

Also Published As

Publication number Publication date
DE10015821A1 (de) 2001-10-18
WO2001075152A2 (fr) 2001-10-11

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