TW201912193A - Medicament delivery device comprising a wipe assembly - Google Patents

Abstract

A medicament delivery device comprising a housing member and a wipe assembly, the wipe assembly comprising a sterilising swab, and a sealing member, wherein the sealing member is attached to the housing member, and wherein the sterilising swab is kept in a sealed compartment by the sealing member, which sealed compartment may be opened to extract the sterilising swab.

Description

Drug delivery device comprising a wiping assembly

The present invention relates to a drug delivery device comprising a wiping assembly, and more particularly to a sterile gauze protected by a sealing member.

Today's drug delivery devices for self-administration require intuitive operation and ease of use. In order to improve patient compliance with a given prescription, it is important that he or she can properly administer the medication according to the prescription and that the medication can be administered without requiring a lengthy manual to be studied. In order to avoid infection, it is advantageous to clean and disinfect the injection site prior to administration of a dose of the drug. However, the user may not be able to obtain clean water, soap, or other cleaning products. Therefore, it is convenient if the components for sterilizing the injection site are contained in the drug delivery device. At the same time, it is important that the function of the conveyor is not reduced or its attractiveness is reduced in any way.

In the present specification, when the term "distal" is used, it means to face away from the dose delivery site. When the term "distal portion/end" is used, it is meant that when the drug delivery device is used, the delivery device is located at a portion/end that is furthest from the dose delivery site, or a portion/end of the component of the delivery device. Correspondingly, when the term "proximal" is used, it means the direction toward the dose delivery site. When the term "proximal portion/end" is used, it means that when the drug delivery device is used, the delivery device is located at the portion/end closest to the dose delivery site, or the portion/end of the member of the delivery device. Furthermore, the term "longitudinal", with or without the term "axis", refers to the direction or axis through which the device or its components are oriented in the longest direction of extension of the device or its components. The term "lateral", with or without the term "axis", means the direction or axis of the device or its components passing through the widest direction of extension of the device or its components. "Side" can also refer to the position of the side of the "longitudinal" slender body. In a similar manner, the term "radial" or "transverse", with or without the term "axis", refers to the direction or axis through which the device or its components are oriented generally perpendicular to the longitudinal direction. For example, "radially facing outward" means facing away from the longitudinal axis. Moreover, unless otherwise stated, the mechanical construction of the device described below and the mechanical interconnection of its components refer to the initial non-activated or inoperative state of the device. In view of the foregoing, it is a general object of the present invention to provide a drug delivery device comprising a wiper assembly. The wiper assembly is easy to use and does not detract from the function or appearance of the delivery device. A main aspect of the invention features a drug delivery device comprising a housing member and a wiper assembly. The wipe assembly includes a sterile gauze and a sealing member. Wherein the sealing member is attached to the housing member, and wherein the sterilizing gauze is retained within the sealed compartment by the sealing member. The sealed compartment can be opened to withdraw the sterile gauze. The sealing member protects the sterile gauze. The sterilizing gauze is a piece of fabric, so the sealing member and the sealed compartment can also have a small profile that does not significantly alter the outer shape of the drug delivery device. The sealed compartment can also be configured to be opened such that the sterile gauze can be easily withdrawn and used to clean the injection site prior to drug delivery. In accordance with another aspect of the invention, the housing member is part of the outer casing of the drug delivery device such that the wiping assembly readily contacts the outer surface of the drug delivery device. According to another aspect of the invention, the housing member is a removable cover of the drug delivery device. For some drug delivery devices, it is preferred to have the wiping assembly disposed on the removable cover member. According to another aspect of the invention, the sterilizing gauze is a wet wipe. Wet wipes are easy to use and produce. According to another aspect of the invention, the wet wipe comprises a disinfecting substance such as alcohol or chlorhexidine. According to another aspect of the invention, the sealing member is a flexible adhesive film that can be removed by peeling the adhesive film from the housing member such that the sealed compartment is opened so that the sterile gauze can be withdrawn. The sterilizing gauze is held in an isolated sealing environment between the viscous membrane and the housing member until the viscous membrane is removed for the first time to open the sealed compartment. After removal of the sterilizing gauze, the viscous film can also be reattached to the housing member to restore the appearance of the housing member and the viscous film. In accordance with an alternative aspect of the invention, the sealing member is a viscous, flexible plastic capsule that forms a sealed compartment. The flexible plastic capsule can be opened to enable the extraction of the sterile gauze. The sterilized gauze is held in an isolated sealed environment within the plastic capsule bag until the plastic capsule is opened for the first time. After removal of the sterile gauze, the plastic capsule bag can be resealed to restore the appearance of the housing member and the plastic capsule bag. According to another aspect of the invention, the sealing member is an adhesive label of a drug delivery device. Therefore, the label can cover the wiping assembly. According to another aspect of the invention, the drug delivery device is an autoinjector, a pen injector, or a safety syringe.

Figures 1a and 1b show an exemplary embodiment of the invention. The drug delivery device 10 therein includes a housing member 15 and a wiper assembly. The wipe assembly includes a sterile gauze 30 and a sealing member 20. The sealing member 20 is attached to the housing member 15, and the sterilizing gauze 30 is held within the sealed compartment by the sealing member 20. The sealed compartment can be opened to withdraw the sterile gauze 30. Disinfecting the gauze 30 is important prior to piercing the user's skin with a drug delivery device, especially in a warm and humid environment where bacteria are susceptible to bacteria. These injection devices may be needle-free syringes or needle-based injection devices, that is, auto-injectors, pen-shaped syringes, safety syringes, and the like. The drug delivery device of the present invention is preferably a single use device. For example, as shown in Figures 1a and 1b, the housing member 15 can be the outer casing of the drug delivery device 10. The outer casing of the drug delivery device is typically a tubular plastic outer casing. The tubular plastic outer casing can be held in the user's hand when the conveyor is operated. In another embodiment, the housing member 15 can be a removable cover (Figs. 3a and 3b) that covers an injection needle (not shown) of the drug delivery device 10. Sealing member 20 can be a one-piece, non-porous, flexible, viscous film that includes a viscous surface 25 along its edges. In another embodiment, the sealing member 20 can comprise a two-piece, non-porous, viscous, flexible plastic capsule. As shown in Figures 2a and 2b, the plastic capsule bag includes an adhesive surface 25 along the mutually facing edges of the two sheets for sealing the bladder. In general, the sealed compartment is formed by the sealing member 20 such that the sealed compartment is substantially flat along the surface of the housing member 15. Thus the sterile gauze 30 can be held directly against the housing member 15 by the one-piece sealing member 20. Thereby, the viscous surface 25 of the sealing member 20 encloses the sterilizing gauze 30 between the housing member 15 and the sealing member 20. In another embodiment, the two-piece sealing member can be a viscous, flexible plastic capsule that is formed by a viscous surface 25 in a sealed compartment or pocket between the two sheets. A viscous bladder containing sterile gauze can be attached to the housing member 15. Because the wiping assembly is flat against the surface of the housing member 15, the sealing member can advantageously include a label for the drug delivery device 10. The tag may contain a logo, or text (eg, a user's indication), or an image. The sterilizing gauze 30 can be a wet wipe that contains a sterilizing substance such as alcohol or chlorhexidine. The sealing member 20 seals the sterile gauze 30 within the sealed compartment from the outside until the compartment is first opened. The lip 27 as illustrated in Figures 3a and 3b can be provided for a user to open a sealed compartment formed by the sealing member 20. In the case of a one-piece sealing member, the viscous film is peeled off from the housing member 15; and in the case of a two-piece capsular bag, the sheet that is not attached to the housing member is attached from the housing to the housing The sheet of the member is peeled off to open the capsule (i.e., the sealed compartment). Preferably, after the sterile gauze 30 is withdrawn, the viscous surface allows the compartment to be closed again so that the appearance of the drug delivery device 10 is not affected or compromised by the open compartment. The appearance is particularly important when the sealing member 20 contains a label. The sterile gauze in the compartment can also be returned to the compartment as waste before it is closed again for later disposal with the used drug delivery device. The user opens the sealed compartment, for example by pulling the lip 27 of the sealing member 20, prior to administering a dose of the drug. The user withdraws the sterile gauze 30 from the compartment and uses gauze to clean the skin at the injection site. Then consider consuming the sterile gauze and returning the gauze back to the compartment or discarding it before closing the compartment again. Next, the drug delivery device 10 can be activated and used to puncture the skin of the injection site without the risk of infecting the user. After use, the drug delivery device 10 can be discarded in a safe manner, such as in a sharp object bucket.

10‧‧‧Drug delivery device

15‧‧‧Shell components

20‧‧‧ Sealing members

25‧‧‧ Viscous surface

27‧‧‧Lip

30‧‧‧Disinfecting gauze

Figures 1a and 1b show conceptual perspective views of an embodiment of the invention. Figures 2a and 2b show detailed views of an embodiment of the invention. Figures 3a and 3b show perspective views of an alternative embodiment of the invention.

Claims (16)

A drug delivery device comprising a housing member and a wiper assembly, the wiper assembly comprising: a sterile gauze; and a sealing member; wherein the sealing member is attached to the housing member, and wherein the sealing member is The sterile gauze remains in the sealed compartment and the sealed compartment can be opened to withdraw the sterile gauze. The drug delivery device of claim 1, wherein the sealed compartment is formed by the sealing member such that the sealed compartment is substantially flat along a surface of the housing member. The drug delivery device of claim 2, wherein the housing member is part of an outer casing of the drug delivery device. The drug delivery device of claim 1, wherein the housing member is a removable cover of the drug delivery device. The drug delivery device of claim 1, wherein the sterile gauze is a wet wipe. The drug delivery device of claim 5, wherein the wet wipe comprises a disinfecting substance such as alcohol or chlorhexidine. The drug delivery device of claim 1, wherein the sealing member is a flexible adhesive film, and the sealing member can be removed by peeling the adhesive film from the housing member such that the sealed compartment is Open to allow the sterile gauze to be withdrawn. The drug delivery device of claim 7, wherein the sterile gauze is held in an insulating sealing environment between the adhesive film and the housing member until the first removal of the adhesive film to open the seal Until the compartment. The drug delivery device of claim 8, wherein after removing the sterile gauze, the adhesive film can be reattached to the housing member to restore the appearance of the housing member and the adhesive film. The drug delivery device of claim 9, wherein the sealing member is a viscous, flexible plastic capsule that forms the sealed compartment, the flexible plastic capsule can be opened to enable extraction Disinfect the gauze. The drug delivery device of claim 10, wherein the sterile gauze is held in an isolated sealed environment within the plastic capsule bag until the plastic capsule bag is opened for the first time. The drug delivery device of claim 11, wherein the plastic capsule bag can be resealed after removal of the sterile gauze to restore the appearance of the housing member and the plastic capsule bag. The drug delivery device of claim 7 or 10, wherein the sealing member comprises an adhesive label of the drug delivery device. The drug delivery device of any one of claims 1 to 13, wherein the drug delivery device is an autoinjector. The drug delivery device of claim 1 to 13, wherein the drug delivery device is a pen-shaped syringe. The drug delivery device of claim 1 to 13, wherein the drug delivery device is a safety syringe.