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SI0831098T1 - Intermediates and process for preparing olanzapine - Google Patents

Intermediates and process for preparing olanzapine

Info

Publication number
SI0831098T1
SI0831098T1 SI9730288T SI9730288T SI0831098T1 SI 0831098 T1 SI0831098 T1 SI 0831098T1 SI 9730288 T SI9730288 T SI 9730288T SI 9730288 T SI9730288 T SI 9730288T SI 0831098 T1 SI0831098 T1 SI 0831098T1
Authority
SI
Slovenia
Prior art keywords
intermediates
preparing olanzapine
olanzapine
preparing
Prior art date
Application number
SI9730288T
Other languages
English (en)
Slovenian (sl)
Inventor
Charles Arthur Bunnell
Samuel Dean Larsen
John Richard Nichols
Susan Marie Reutzel
Gregory Alan Stephenson
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21832120&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI0831098(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of SI0831098T1 publication Critical patent/SI0831098T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SI9730288T 1996-09-23 1997-09-22 Intermediates and process for preparing olanzapine SI0831098T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2648796P 1996-09-23 1996-09-23
EP97307383A EP0831098B1 (en) 1996-09-23 1997-09-22 Intermediates and process for preparing olanzapine

Publications (1)

Publication Number Publication Date
SI0831098T1 true SI0831098T1 (en) 2002-04-30

Family

ID=21832120

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9730288T SI0831098T1 (en) 1996-09-23 1997-09-22 Intermediates and process for preparing olanzapine

Country Status (36)

Country Link
US (1) US6020487A (tr)
EP (1) EP0831098B1 (tr)
JP (2) JP2001500877A (tr)
KR (1) KR100560015B1 (tr)
CN (1) CN1122036C (tr)
AR (1) AR013838A1 (tr)
AT (1) ATE209208T1 (tr)
AU (1) AU719441B2 (tr)
BR (1) BR9712100A (tr)
CA (1) CA2265712C (tr)
CO (1) CO4910140A1 (tr)
CZ (1) CZ299248B6 (tr)
DE (1) DE69708428T2 (tr)
DK (1) DK0831098T3 (tr)
EA (1) EA001642B1 (tr)
EG (1) EG23861A (tr)
ES (1) ES2166051T3 (tr)
HK (1) HK1009807A1 (tr)
HU (1) HU226484B1 (tr)
ID (1) ID27275A (tr)
IL (1) IL128962A (tr)
IN (1) IN187156B (tr)
MY (1) MY125565A (tr)
NO (1) NO323980B1 (tr)
NZ (1) NZ334448A (tr)
PE (1) PE110398A1 (tr)
PL (3) PL196068B1 (tr)
PT (1) PT831098E (tr)
RS (1) RS49598B (tr)
SI (1) SI0831098T1 (tr)
SV (1) SV1997000081A (tr)
TR (1) TR199900640T2 (tr)
TW (1) TW470746B (tr)
UA (1) UA59371C2 (tr)
WO (1) WO1998012199A1 (tr)
ZA (1) ZA978515B (tr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0300875A3 (en) * 2000-08-31 2005-09-28 Reddy S Lab Ltd Hyderabad Dr Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine
US6740753B2 (en) 2001-01-04 2004-05-25 Geneva Pharmaceuticals, Inc. Olanzapine crystal modification
WO2003037903A1 (en) * 2001-10-29 2003-05-08 Dr. Reddy's Laboratories Ltd. Olanzapine dihydrate-ii a process for its preparation and use thereof
JP4530664B2 (ja) 2001-12-24 2010-08-25 サン・ファーマシューティカル・インダストリーズ・リミテッド ２−メチル−４−（４−メチル−１−ピペラジニル）−１０Ｈ−チエノ［２，３−ｂ］［１，５］ベンゾジアゼピンの結晶形Ｉ、この結晶形Ｉの製造方法、及び医薬組成物
AU2003243153A1 (en) * 2002-04-23 2003-11-10 Dr. Reddy's Laboratories Limited Novel crystalline polymorph form-vi of olanzapine and a process for preparation thereof
SI1513846T1 (sl) * 2002-05-31 2011-11-30 Sandoz Ag Postopek za pripravo olanzapina form I
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
US7323459B2 (en) 2002-12-24 2008-01-29 Teva Pharmaceutical Industries Ltd. Crystal forms, methods for their preparation and method for preparation of olanzapine
CA2546200A1 (en) * 2003-11-18 2005-06-02 3M Innovative Properties Company Olanzapine containing transdermal drug delivery compositions
DE602004014264D1 (de) * 2003-12-22 2008-07-17 Teva Pharma Verfahren zur herstellung von olanzapin
WO2005070938A1 (en) 2004-01-27 2005-08-04 Synthon B.V. Stable salts of olanzapine
US20070072845A1 (en) * 2004-02-19 2007-03-29 Davuluri Rammohan Rao Process for the preparation of olanzapine form 1 useful as antipsychotic drug
WO2006006185A1 (en) * 2004-07-14 2006-01-19 Shasun Chemicals And Drugs Limited Improved process for making form i of olanzapine.
ES2253091B1 (es) 2004-07-27 2007-02-01 Inke, S.A. Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
DE112005000641T5 (de) * 2004-09-06 2007-09-06 Shasun Chemicals and Drugs Ltd., Chennai Neues Verfahren zur Herstellung einer pharmazeutisch reinen polymorphen Form I von Olanzapin
CA2587710C (en) * 2004-11-16 2014-10-21 Elan Pharma International Ltd. Injectable nanoparticulate olanzapine formulations
US7834176B2 (en) 2006-01-26 2010-11-16 Sandoz Ag Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E
CA2591644A1 (en) * 2007-06-14 2008-12-14 Apotex Pharmachem Inc. Novel processes to form-i of olanzapine
EP2486913A1 (en) 2011-02-14 2012-08-15 Labtec GmbH Rapidly disintegrating oral film formulation for Olanzapin
JP6008734B2 (ja) * 2012-12-20 2016-10-19 株式会社トクヤマ オランザピンｉｉ型結晶の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302716A (en) * 1986-01-16 1994-04-12 Schering Corporation Fused benzazepines
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
US5229382A (en) * 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
EP0582368B1 (en) * 1992-05-29 2001-01-24 Eli Lilly And Company Limited Thienobenzodiazepine derivatives for treatment of CNS disorders
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5602124A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. 5-HT2 receptor ligands
EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
EG24221A (en) * 1995-03-24 2008-11-10 Lilly Co Eli Process for preparing olanzapine
US5631250A (en) * 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
US5637584A (en) * 1995-03-24 1997-06-10 Eli Lilly And Company Solvate of olanzapine
KR100516088B1 (ko) * 1996-09-23 2005-09-22 일라이 릴리 앤드 캄파니 올란자핀 이수화물 ｄ

Also Published As

Publication number Publication date
NO323980B1 (no) 2007-07-30
EG23861A (en) 2007-11-18
KR100560015B1 (ko) 2006-03-15
MY125565A (en) 2006-08-30
DK0831098T3 (da) 2002-05-21
CN1122036C (zh) 2003-09-24
EP0831098A2 (en) 1998-03-25
TW470746B (en) 2002-01-01
NZ334448A (en) 2000-08-25
WO1998012199A1 (en) 1998-03-26
HUP0000066A2 (hu) 2000-06-28
CO4910140A1 (es) 2000-04-24
EP0831098B1 (en) 2001-11-21
ES2166051T3 (es) 2002-04-01
HK1009807A1 (en) 1999-06-11
CA2265712C (en) 2006-10-31
EA001642B1 (ru) 2001-06-25
TR199900640T2 (tr) 1999-06-21
PE110398A1 (es) 1999-01-14
HUP0000066A3 (en) 2000-11-28
CA2265712A1 (en) 1998-03-26
PL196068B1 (pl) 2007-12-31
KR20000048520A (ko) 2000-07-25
RS49598B (sr) 2007-06-04
AU719441B2 (en) 2000-05-11
PL196069B1 (pl) 2007-12-31
ATE209208T1 (de) 2001-12-15
JP2009242407A (ja) 2009-10-22
IL128962A0 (en) 2000-02-17
DE69708428T2 (de) 2002-07-04
BR9712100A (pt) 1999-08-31
IN187156B (tr) 2002-02-16
ZA978515B (en) 1999-03-23
PT831098E (pt) 2002-04-29
YU15599A (sh) 2001-12-26
NO991382D0 (no) 1999-03-22
CZ99099A3 (cs) 1999-11-17
DE69708428D1 (de) 2002-01-03
CN1234802A (zh) 1999-11-10
PL194565B1 (pl) 2007-06-29
NO991382L (no) 1999-03-22
IL128962A (en) 2003-01-12
EP0831098A3 (en) 1998-04-29
CZ299248B6 (cs) 2008-05-28
ID27275A (id) 2001-03-22
SV1997000081A (es) 1999-01-14
AR013838A1 (es) 2001-01-31
HU226484B1 (en) 2009-03-02
JP2001500877A (ja) 2001-01-23
EA199900326A1 (ru) 1999-08-26
US6020487A (en) 2000-02-01
AU4484197A (en) 1998-04-14
UA59371C2 (uk) 2003-09-15
PL332482A1 (en) 1999-09-13

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