LU506532B1 - A Traditional Chinese Medicine Composition For Beautifying And Removing pigmentation And An Application Thereof - Google Patents
A Traditional Chinese Medicine Composition For Beautifying And Removing pigmentation And An Application Thereof Download PDFInfo
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- LU506532B1 LU506532B1 LU506532A LU506532A LU506532B1 LU 506532 B1 LU506532 B1 LU 506532B1 LU 506532 A LU506532 A LU 506532A LU 506532 A LU506532 A LU 506532A LU 506532 B1 LU506532 B1 LU 506532B1
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- radix
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- 239000000203 mixture Substances 0.000 title claims abstract description 16
- 229940079593 drug Drugs 0.000 title description 6
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- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 9
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- 238000002791 soaking Methods 0.000 claims description 3
- 239000006071 cream Substances 0.000 claims description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 abstract description 24
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- XUCIJNAGGSZNQT-JHSLDZJXSA-N (R)-amygdalin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O[C@@H](C#N)C=2C=CC=CC=2)O1 XUCIJNAGGSZNQT-JHSLDZJXSA-N 0.000 description 1
- IQVQXVFMNOFTMU-FLIBITNWSA-N (Z)-ligustilide Chemical compound C1CC=CC2=C1C(=C/CCC)/OC2=O IQVQXVFMNOFTMU-FLIBITNWSA-N 0.000 description 1
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- VIHAEDVKXSOUAT-UHFFFAOYSA-N but-2-en-4-olide Chemical compound O=C1OCC=C1 VIHAEDVKXSOUAT-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
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- A61Q19/08—Anti-ageing preparations
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
The invention provides a traditional Chinese medicine composition for beautifying and removing pigmentation and an application thereof, the composition is composed of Radix Angelicae Sinensis, Fructus Schisandrae Chinensis, Radix et Rhizoma ginseng, Radix Rehmanniae Praeparata, Rhizoma Polygonati, Rhizoma Polygonati Odorati, Semen Persicae, Rhizoma Chuanxiong, Radix et Rhizoma Salviae Miltiorrhizae, Radix et Rhizoma Glycyrrhizae; each medicine acts synergistically, so that the invention can nourish blood and promote blood circulation, dispel stasis and eliminate spots, and can effectively inhibit the activity of tyrosinase, suppress melanin synthesis, and reduce melanin deposition from the source; in addition, it can also improve the microcirculation of the skin, keep the capillaries unobstructed, regulate facial tissue repair and regeneration to achieve cleansing, whitening, and skin care; it can reduce local inflammatory stimulation, and can target multiple targets: removing pigmentation, reducing inflammation and acne to achieve beauty and skin care.
Description
SPECIFICATION
LU506532
A Traditional Chinese Medicine Composition For Beautifying And
Removing pigmentation And An Application Thereof
[0001] The invention relates to the technical field of skin care cosmetics, in particular to a traditional Chinese medicine composition for beautifying and removing pigmentation and an application thereof.
[0002] As age increases and the pressure of life increases, coupled with environmental pollution and the damaging effects of ultraviolet radiation on facial skin, melanin continues to deposit, causing the skin to become rough and dull. When melanin grows too fast and is unevenly distributed, it leads to localized skin darkening and pigmentation, resulting in the formation of dark spots. As age increases, the likelihood of developing skin pigmentation significantly increases, becoming a major concern for skincare. Therefore, freckle removal products have become increasingly popular. At present, there are various types of freckle removal cosmetics available in the market. However, many of them contain harmful substances such as mercury, lead, and hormones, and often rely on covering up or “thinning” the skin to achieve freckle removal and whitening effects. These products have significant toxic side effects and can cause skin dependence and allergic reactions. Once discontinued, the skin may become dull and develop scars. In some cases, individuals may experience facial redness, swelling, and even ulceration. In contrast, traditional Chinese medicine is gradually becoming more and more popular because it is natural and has no side effects. When used in cosmetics and medicines, it can achieve dual effects of skin treatment and skin care. In the case of freckle removal, besides the impact of ultraviolet radiation, local inflammation stimulation can also stimulate the body to release signals that activate melanin formation, leading to excessive melanin production and resulting in pigmentation (spots) and a loss of skin radiance (dullness). However, some current traditional Chinese medicine products targeting freckle removal have a single target and can not achieve satisfactory results.
SPECIFICATION
LU506532
[0003] Therefore, in view of the above shortcomings, the invention provides a traditional
Chinese medicine composition for beautifying and removing pigmentation and an application thereof, which can effectively remove pigmentation, reduce inflammation and acne, and achieve beauty and skin care.
[0004] The technical scheme of the invention is as follow:
[0005] A traditional Chinese medicine composition for beautifying and removing pigmentation comprises the following raw materials in parts by weight:
[0006] 35-55 parts of Radix Angelicae Sinensis, 15-35 parts of Fructus Schisandrae Chinensis, 40-60 parts of Radix et Rhizoma ginseng, 40-60 parts of Radix Rehmanniae Praeparata, 5-25 parts of Rhizoma Polygonati, 25-45 parts of Rhizoma Polygonati Odorati, 8-28 parts of
Semen Persicae, 15-35 parts of Rhizoma Chuanxiong, 10-30 parts of Radix et Rhizoma
Salviae Miltiorrhizae, 15-35 parts of Radix et Rhizoma Glycyrrhizae.
[0007] Preferably, it comprises the following raw materials in parts by weight:
[0008] 45 parts of Radix Angelicae Sinensis, 25 parts of Fructus Schisandrae Chinensis, 50 parts of Radix et Rhizoma ginseng, 50 parts of Radix Rehmanniae Praeparata, 15 parts of
Rhizoma Polygonati, 35 parts of Rhizoma Polygonati Odorati, 18 parts of Semen Persicae, 25 parts of Rhizoma Chuanxiong, 20 parts of Radix et Rhizoma Salviae Miltiorrhizae, 25 parts of
Radix et Rhizoma Glycyrrhizae.
[0009] The invention also provides an application of the traditional Chinese medicine composition for beautifying and removing pigmentation, it can be used in the preparation of products for beautifying and removing pigmentation.
[0010] Further, the products for beautifying and removing pigmentation are essence water, facial cream or skin care water.
[0011] Preferably, the product for beautifying and removing pigmentation is essence water.
[0012] Further, the preparation method of the essence water is as follow:
[0013] 1) soaking each raw material in pure glutinous rice wine for more than 6 months, filtering, taking the filtrate, sterilizing and disinfecting it to obtain the final product.
[0014] Among the raw materials used in the invention:
[0015] Radix Angelicae Sinensis promotes blood circulation, dissipates blood stasis, reduces
SPECIFICATION
LU506532 swelling, and discharges pus; its external use can promote blood circulation and inhibit the activity of tyrosinase; and it contains n-butenolide and ligustilide, which have certain antibacterial and anti-inflammatory effects.
[0016] Fructus Schisandrae Chinensis nourishes qi and promotes the production of body fluid, nourishes Yin and invigorates kidney, calms the heart and soothes the nerves; its external use can stop bleeding, eliminates dampness and astringes sores, and can also have sterilizing and antibacterial effects.
[0017] Radix et Rhizoma ginseng nourishes qi and blood, clears heat and promotes the production of body fluid; its external use can dilate the capillaries of the skin, promote blood circulation, and increase skin nutrition; the active ingredients it contains can also inhibit the reduction of melanin, making the skin white and smooth; it is rich in saponins, trace elements, and minerals that are necessary for skin metabolism, and is needed for skin growth and division; when used externally, it can also achieve the effect of removing wrinkles.
[0018] Radix Rehmanniae Praeparata promotes blood circulation and removes blood stasis, nourishes yin and kidneys, nourishes blood and regulates menstruation; its external use can have anti-aging, acne and other effects.
[0019] Rhizoma Polygonati nourishes yin and moisturizes the lungs, nourishes the spleen and qi, promotes blood circulation and removes blood stasis; its external use can delay the aging process of the skin and the shrinkage of collagen fibers, and can nourish the skin and slow down aging.
[0020] Rhizoma Polygonati Odorati is nourishing, calming and soothing the nerves; it is rich in vitamins and other nutrients, which can effectively relieve rough and dry skin conditions; its external use can have whitening, hydrating, moisturizing and other effects.
[0021] Semen Persicae promotes blood circulation and removes blood stasis; its external use can enhance local blood circulation, and its rich content of amygdalin can play a bactericidal and anti-inflammatory role.
[0022] Rhizoma Chuanxiong promotes blood circulation and removes blood stasis, promotes qi circulation and relieves pain; its external use can prevent the production of melanin in the human body, lighten skin pigmentation, promote skin metabolism, prevent the growth of skin
SPECIFICATION
LU506532 inflammation, and delay skin aging.
[0023] Radix et Rhizoma Salviae Miltiorrhizae promotes blood circulation and removes blood stasis, dredges the meridians and relieves pain; its external use can improve the microcirculation of the skin, unblock the capillaries of the skin, regulate the repair and regeneration of skin tissue, thereby achieving the effects of skin cleansing, acne and blemish removal.
[0024] Radix et Rhizoma Glycyrrhizae reduces inflammation, soothes skin, and lightens dark spots.
[0025] By adopting the invention, it has the following advantageous effects:
[0026] Throughout the invention, the main drugs of the invention are Radix Angelicae
Sinensis, Radix et Rhizoma ginseng, and Radix Rehmanniae Praeparata, which can nourish blood and promote blood circulation, dispel stasis and eliminate spots, and can effectively inhibit the activity of tyrosinase, suppress melanin synthesis, and reduce melanin deposition from the source; in addition, it can also improve the microcirculation of the skin, keep the capillaries unobstructed, regulate facial tissue repair and regeneration to achieve cleansing, whitening, and skin care; Rhizoma Chuanxiong, Radix et Rhizoma Glycyrrhizae sterilize and reduce inflammation, reduce local inflammatory stimulation, and together with the main drugs to reduce the deposition of melanin and reduce the occurrence of spots; Fructus Schisandrae
Chinensis, Semen Persicae, Rhizoma Chuanxiong, Radix et Rhizoma Salviae Miltiorrhizae all help the main drugs to promote blood circulation and remove blood stasis, improve the microcirculation of the skin, and lighten spots, Rhizoma Polygonati Odorati nourishes and calms the skin to hydrate and moisturize the skin; the synergy effect of each raw material can target multiple targets: lightening and removing pigmentation, whitening skin, and reducing inflammation and acne to achieve beauty and skin care.
[0027] In order to explain the embodiments of the invention or the technical schemes in the prior art more clearly, the accompanying drawings needed to be used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the accompanying drawings in the following description are only some embodiments of the invention.
SPECIFICATION
LU506532
[0028] FIG. 1 shows photos of the pigmentation removal process of the typical case in the embodiment.
[0029] Reference will now be provided in detail to embodiments of the invention, one or more embodiments of which are described below. Each embodiment is provided by way of explanation, not limitation of the invention. In fact, it will be apparent to those skilled in the art that various modifications and variations can be made in the invention without departing from the scope or spirit of the invention. For example, features illustrated or described as part of one embodiment can be used in another embodiment to yield yet further embodiments.
[0030] Therefore, it is intended that the invention cover such modifications and variations as come within the scope of the appended claims and their equivalents. Other objects, features, and aspects of the invention are disclosed in, or are apparent from, the following detailed description. Those of ordinary skill in the art should understand that this discussion is merely a description of exemplary embodiments and is not intended to limit the broader aspects of the invention. The invention will be further described below in combination with the embodiments.
[0031] Embodiment 1: a traditional Chinese medicine composition for beautifying and removing pigmentation comprises the following raw materials in parts by weight:
[0032] 45 parts of Radix Angelicae Sinensis, 25 parts of Fructus Schisandrae Chinensis, 50 parts of Radix et Rhizoma ginseng, 50 parts of Radix Rehmanniae Praeparata, 15 parts of
Rhizoma Polygonati, 35 parts of Rhizoma Polygonati Odorati, 18 parts of Semen Persicae, 25 parts of Rhizoma Chuanxiong, 20 parts of Radix et Rhizoma Salviae Miltiorrhizae, 25 parts of
Radix et Rhizoma Glycyrrhizae.
[0033] In this embodiment, the above raw materials are prepared into external coating essence water, which is prepared as follows:
[0034] 1) soaking each raw material in about 1kg of pure glutinous rice wine at 55 degrees for more than 6 months, filtering, taking the filtrate, sterilizing and disinfecting it to obtain the final product.
[0035] When using it specifically, applying the essence water prepared above to the spots or
SPECIFICATION
LU506532 dull areas of the face twice a day; after applying the essence water each time, massaging it to allow it to be absorbed; after the essence water stays on the face for 6 hours, rinsing the face with clean water.
[0036] Note: people with facial skin allergic to alcohol should use with caution.
[0037] Control group: a traditional Chinese medicine composition comprises the following raw materials in parts by weight: 45 parts of Radix Angelicae Sinensis, 25 parts of Fructus
Schisandrae Chinensis, 50 parts of Radix et Rhizoma ginseng, 50 parts of Radix Rehmanniae
Praeparata, 15 parts of Rhizoma Polygonati, 35 parts of Rhizoma Polygonati Odorati, 18 parts of Semen Persicae, 20 parts of Radix et Rhizoma Salviae Miltiorrhizae.
[0038] It is prepared into essence water in the same manner as Embodiment 1.
[0039] Safety test of the essence water of this embodiment:
[0040] A total of 40 volunteers, including 12 males and 28 females aged between 25 and 45, who have no allergies to alcohol, were selected. The essence water was applied to the inner side of the volunteers’ arms, approximately Scm from the base of the palm; the application was done once in the morning and once in the evening, continuously for two weeks. During this period, volunteers provided feedback on whether there were any localized redness or peeling of the skin at the application site. The results showed that none of the volunteers experienced redness or skin peeling at the application site.
[0041] Embodiment 2: clinical experiment on skin whitening and pigmentation removal
[0042] A total of 50 volunteers, including 10 males and 40 females aged between 16 and 52, who have no allergies to alcohol but have varying degrees of facial skin dullness due to irregular lifestyles, were selected. The volunteers were randomly divided into two groups: an embodiment group and a control group, with 25 participants in each group. The volunteers in the embodiment group and the control group applied the essence water of the embodiment 1 and the control group respectively, on their faces twice daily; after continuous use for 1.5 months, a skin testing device was used to measure the melanin level in the volunteers’ facial skin to evaluate the effect.
[0043] Effect standard:
[0044] significantly effective: melanin value is lower than 20;
SPECIFICATION
LU506532
[0045] effective: melanin value 1s 20-30;
[0046] ineffective: melanin value is 30 or above. Effective rate = (effective + significantly effective) * 100 / total number of people
[0047] The results are shown as follows:
[0048] embodiment group: 11 people were significantly effective, 10 people were effective, 4 people were ineffective, and the effective rate was 84%;
[0049] control group: 7 people were significantly effective, 11 people were effective, 7 people were ineffective, and the effective rate was 72%.
[0050] A total of 60 female volunteers aged between 16 and 55, who have no allergies to alcohol, were selected. All volunteers have facial pigmentation, including 12 with chloasma, 14 with freckles, and 34 with sunspots. Additionally, all volunteers had varying degrees of acne on their faces. The volunteers were randomly divided into two groups: an embodiment group and a control group, with 30 participants in each group. The volunteers in the embodiment group and the control group applied the essence water of the embodiment 1 and the control group respectively, on their faces twice daily; after continuous use for 1.5 months, the effect were evaluated.
[0051] Effect standard:
[0052] significantly effective: pigmentation was significantly lightened or faded by more than 90%;
[0053] effective: pigmentation fade by more than 50%;
[0054] ineffective: if there is no change before and after treatment, it is considered ineffective.
Effective rate = (effective + significantly effective) * 100 / total number of people
[0055] The results are shown as follows:
[0056] embodiment group: 16 people were significantly effective, 12 people were effective, 2 people were ineffective, and the effective rate was 93.33%;
[0057] control group: 11 people were significantly effective, 14 people were effective, 5 people were ineffective, and the effective rate was 83.33%.
[0058] The volunteers were observed and found that after 2 weeks of use, 97% of the volunteers in the embodiment group had their acne subsided; 91% of the volunteers in the
SPECIFICATION
LU506532 control group had their acne subsided.
[0059] Embodiment 3: typical case
[0060] Ms. Zhang, female, 35 years old, had chloasma on her left and right faces, dull facial skin, and sallow complexion. She applied the essence water of Embodiment 1 on her face for about 3 courses. One course of treatment lasted for 20 days. Her skin tone was obviously brightened and chloasma was significantly reduced, as shown in FIG. 1.
[0061] The technical features of the above-described embodiments can be combined in any way. To simplify the description, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered to be within the scope of this specification.
Claims (6)
1. À traditional Chinese medicine composition for beautifying and removing pigmentation, wherein it comprises the following raw materials in parts by weight: 35-55 parts of Radix Angelicae Sinensis, 15-35 parts of Fructus Schisandrae Chinensis, 40-60 parts of Radix et Rhizoma ginseng, 40-60 parts of Radix Rehmanniae Praeparata, 5-25 parts of Rhizoma Polygonati, 25-45 parts of Rhizoma Polygonati Odorati, 8-28 parts of Semen Persicae, 15-35 parts of Rhizoma Chuanxiong, 10-30 parts of Radix et Rhizoma Salviae Miltiorrhizae, 15-35 parts of Radix et Rhizoma Glycyrrhizae.
2. A traditional Chinese medicine composition for beautifying and removing pigmentation according to claim 1, wherein it comprises the following raw materials in parts by weight: parts of Radix Angelicae Sinensis, 25 parts of Fructus Schisandrae Chinensis, 50 parts of Radix et Rhizoma ginseng, 50 parts of Radix Rehmanniae Praeparata, 15 parts of Rhizoma Polygonati, 35 parts of Rhizoma Polygonati Odorati, 18 parts of Semen Persicae, 25 parts of Rhizoma Chuanxiong, 20 parts of Radix et Rhizoma Salviae Miltiorrhizae, 25 parts of Radix et Rhizoma Glycyrrhizae.
3. The application of a traditional Chinese medicine composition for beautifying and removing pigmentation according to claim 1 or 2, wherein it can be used in the preparation of products for beautifying and removing pigmentation.
4. The application of a traditional Chinese medicine composition for beautifying and removing pigmentation according to claim 3, wherein the products for beautifying and removing pigmentation are essence water, facial cream or skin care water.
5. The application of a traditional Chinese medicine composition for beautifying and removing pigmentation according to claim 4, wherein the product for beautifying and removing pigmentation is essence water.
6. The application of a traditional Chinese medicine composition for beautifying and removing pigmentation according to claim 5, wherein the preparation method of the essence water is as follow: 1) soaking each raw material in pure glutinous rice wine for more than 6 months, filtering, taking the filtrate, sterilizing and disinfecting it to obtain the final product.
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LU (1) | LU506532B1 (en) |
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